续断来源考证、化学成分及药理作用综述  

Textual Research of Source,Chemical Constituents and Pharmacological Action of RadixDipsaci:A Review

作　　者：代琪 叶臻 叶俏波[3] 雷蕾 DAI Qi;YE Zhen;YE Qiao-bo;LEI Lei(Chengdu Institute for Food and Drug Control,NMPA Key Laboratory for Quality Monitoring and Evaluation of Traditional Chinese Medicine,Sichuan Chengdu 610045,China;Basic Medical College,Chengdu University of Traditional Chinese Medicine,Sichuang Chengdu 611137,China;Chengdu University of Traditional Chinese Medicine,Sichuan Chengdu 611137,China)

机构地区：[1]成都市食品药品检验研究院国家药品监督管理局中药材质量监测评价重点实验室,四川成都610045 [2]成都中医药大学基础医学院,四川成都611137 [3]成都中医药大学方剂学教研室,四川成都611137

出　　处：《中国药物评价》2020年第6期432-436,共5页Chinese Journal of Drug Evaluation

基　　金：四川省国际科技创新合作/港澳台科技创新合作项目(项目编号:2020YFH0193;项目名称:《德国药品法典》中药质量标准示范研究)。

摘　　要：目的:对续断的来源考证、化学成分和药理作用进行综述,回顾续断确定来源的发展历程,并通过化学成分和药理作用的总结,为续断的考证、进一步研究及应用提供参考。方法:以“续断”、“川续断”、“考证”、“化学成分”、“药理作用”等作为关键词,在中国知网、中国生物医学文献服务系统、万方医学网、Pubmed、维普网等数据库进行检索,整理相关文献并进行综述。结果与结论:目前,续断现行版药典来源是川续断科植物川续断Dipsacus asper Wall.Ex Henry的干燥根。川续断化学成分包含三萜皂苷类、环烯醚萜类、生物碱类、酚醛酸类及其他成分,具有预防复发性自然流产、骨保护、神经保护、肝脏保护、抗衰老等药理作用。Objective:This paper aims to review the textual research of source,chemical constituents and pharmacological activities of RadixDipsaci,which offers references for further research and application.Methods:Using"RadixDipsaci","SichuanRadixDipsaci","Textual Research of Source","chemical constituents","pharmacological action"as keywords,the related literatures in recent years were retrieved from CNKI,wanfang.com and vip.com.Results&Conclusion:The specified source of Radix Dipsaci of Pharmacopoeia of the People′s Republic of China is Dipsacus asper Wall.Ex Henry.Triterpenoids,Iridoids,akaloids,Phenolic acids are the key chemical constituents and preventing spontaneous abortion,bones protection,nerves protection,liver protection and anti-aging are the main pharmacological action.

关 键 词：续断 来源 化学成分 药理作用 

分 类 号：R962[医药卫生—药理学]