克拉霉素片致迟发型过敏反应1例分析  

Analysis of One Case of Delayed Anaphylaxis Induced by Clarithromycin Tablets

作　　者：刘静静[1] 王亦磊[1] 王彤[1] 康艳生 张伟[1] 徐小亚[1] 常人元 王晓琴[1] LIU Jingjing;WANG Yilei;WANG Tong;KANG Yansheng;ZHANG Wei;XU Xiaoya;CHANG Renyuan;WANG Xiaoqin(Department of Pharmacy,The First Hospital of Yulin,Yulin Shaanxi 719000,China)

机构地区：[1]榆林市第一医院药剂科,陕西榆林719000

出　　处：《中国药物警戒》2020年第12期946-948,共3页Chinese Journal of Pharmacovigilance

摘　　要：目的分析1例克拉霉素致迟发型过敏反应,为临床安全用药提供参考。方法对患者服用的药物进行关联性评价,并对其进行文献分析。结果患者敏感体质,迟发型过敏反应为克拉霉素所致。经过积极抗过敏治疗,患者痊愈。结论克拉霉素为低敏性药物,亦可致迟发型过敏反应,但一般症状较轻微,敏感体质慎用。Objective To analyze one case of delayed anaphylaxis induced by clarithromycin and provide safe references for clinical prescriptions.Methods To evaluate the relevance between drugs taken by patients and analyze the literature.Results The patient was sensitive constitution and delayed allergic reaction were caused by clarithromycin,after the antiallergic treatment,the patients recovered.Conclusion Clarithromycin has a low incidence of anaphylaxis and can caused delayed anaphylaxis with mild general symptoms.The patient of sensitive constitution should be used with caution.

关 键 词：克拉霉素 药品不良反应 迟发型过敏反应 

分 类 号：R969.3[医药卫生—药理学]