依托咪酯应用于心血管患者麻醉诱导的临床疗效观察  

Observation of the clinical efficacy of etomidate applied to anesthesia induction in cardiovascular patients

作　　者：王辉[1] 岳彬[1] 郝晓燕[1] WANG Hui;YUE Bin;HAO Xiaoyan(Department of Anesthesiology,Dalian Friendship Hospital,Dalian,Liaoning,116011,China)

机构地区：[1]大连市友谊医院麻醉科,辽宁大连116011

出　　处：《当代医学》2021年第3期62-64,共3页Contemporary Medicine

摘　　要：目的探讨分析心血管患者麻醉诱导中使用依托咪酯的效果。方法回顾性分析2015年1月至2019年10月本院收治的84例心血管患者,采用随机抽取法分为研究组和对照组,各42例。研究组麻醉诱导后使用依托咪酯,对照组麻醉诱导时使用依托咪酯。比较两组不同时间点(诱导前、麻醉诱导后1 min、3 min和插管后1 min、3 min和拔管时)的平均动脉血压、心率和SPO2值变化及麻醉效果和麻醉后VAS评分。结果诱导前,两组平均动脉血压、心率和SPO2值比较差异无统计学意义;麻醉诱导后1 min、3 min和插管后1 min、3 min,研究组平均动脉血压低于对照组(P<0.05);两组麻醉诱导后1 min、3 min和插管后1 min、3 min和拔管时心率和SPO2值比较差异无统计学意义,与诱导前比较差异无统计学意义。两组麻醉效果比较差异无统计学意义,研究组麻醉后VAS评分低于对照组(P<0.05)。结论在心血管患者麻醉诱导后使用依托咪酯麻醉效果显著,对患者平均动脉血压无明显影响,可降低麻醉后疼痛,值得临床推广应用。Objective To explore and analyze the effect of etomidate in induction of anesthesia in cardiovascular patients.Methods A retrospective analysis of 84 cardiovascular patients admitted to our hospital from January 2015 to October 2019 was randomized and divided into study group and control group,with 42 cases in each group.The study group used etomidate after induction of anesthesia,and the control group used etomidate during induction of anesthesia.The changes in mean arterial blood pressure,heart rate and SPO2 values at different time points(before induction,1 min,3 min after induction of anesthesia,1 min,3 min after intubation and extubation)were compared between the two groups,as well as the effect of anesthesia and VAS score after anesthesia.Results Before induction,there was no statistically significant difference in the mean arterial blood pressure,heart rate and SPO2 value between the two groups.1 min,3 min after induction of anesthesia and 1 min,3 min after intubation,the average arterial blood pressure of the study group was lower than that of the control group(P<0.05).There was no significant difference in heart rate and SPO2 between the two groups at 1 min,3 min after induction of anesthesia,1 min,3 min after intubation,and heart rate and SPO2 value at extubation,and there was no significant difference between the two groups before induction.There was no statistically significant difference in the effects of anesthesia between the two groups.The VAS score of the study group was lower than that of the control group(P<0.05).Conclusion Etomidate has a significant anesthesia effect after induction of anesthesia in cardiovascular patients,and has no significant effect on the patients'mean arterial blood pressure.It can reduce pain after anesthesia and is worthy of clinical application.

关 键 词：心血管 麻醉诱导 依托咪酯 平均动脉血压 VAS评分 麻醉效果 

分 类 号：R614[医药卫生—麻醉学]