慢性乙型肝炎发展过程中的免疫失衡  

Immunity Imbalance in the Development of Chronic Hepatitis B

作　　者：张楚悦 卓越[1] 田桦[1] Zhang Chuyue;Zhuo Yue;Tian Hua(The First Affiliated Hospital of Jiamusi University,Jiamusi 154003,China)

机构地区：[1]佳木斯大学附属第一医院,黑龙江佳木斯154003

出　　处：《广东化工》2020年第23期60-60,62,共2页Guangdong Chemical Industry

摘　　要：乙型肝炎病毒(HBV)感染是导致慢性肝炎,肝纤维化,肝硬化和肝细胞癌(HCC)的主要危险因素之一。大量临床研究表明,慢性HBV持续感染会引起先天性和适应性免疫反应功能障碍,涉及单核细胞/巨噬细胞,髓样来源的抑制细胞(MDSC),NK细胞,T细胞等。本篇综述对慢性乙型肝炎发展过程中的免疫失衡进行阐述。Hepatitis B virus(HBV) infection is one of the main risk factors for chronic hepatitis, liver fibrosis, cirrhosis and hepatocellular carcinoma(HCC). A large number of clinical studies have shown that chronic HBV persistent infection can cause innate and adaptive immune response dysfunction, involving monocytes/macrophages, myeloid-derived suppressor cells(MDSC), NK cells, T cells, etc. This review describes the immune imbalance in the development of chronic hepatitis B.

关 键 词：乙型病毒性肝炎 特异性免疫反应 细胞因子 

分 类 号：TQ[化学工程]