依达拉奉联合亚低温康复护理对重型颅脑损伤患者PT、APTT及NIHSS评分的影响  

Effect of Edaravone Combined with Mild Hypothermia Rehabilitation Nursing on PT,APTT and NIHSS Scores in Patients with Severe Craniocerebral Injury

作　　者：李传宏[1] 王景阳 LI Chuanhong;WANG Jingyang(Department of Neurosurgery,Nanyang Second People's Hospital,Nanyang Henan 473000,China)

机构地区：[1]南阳市第二人民医院神经外科,河南南阳473000

出　　处：《药品评价》2020年第21期33-35,共3页Drug Evaluation

摘　　要：目的:研究依达拉奉联合亚低温康复护理对重型颅脑损伤患者凝血酶原时间(PT)、活化部分凝血酶时间(APTT)及脑卒中量表(NIHSS)评分的影响。方法:选取100例重型颅脑损伤患者,按随机数字法分为观察组(n=50)和对照组(n=50)。对照组给予常规治疗及护理,观察组在对照组基础上给予依达拉奉联合亚低温康复护理,观察两组凝血功能、NIHSS评分及预后恢复情况。结果:治疗后,两组APTT、PT水平均升高(P<0.05),且观察组低于对照组(P<0.05);观察组NIHSS评分低于对照组(P<0.05),恢复满意度高于对照组(P<0.05)。结论:神经外科重型颅脑损伤患者应用依达拉奉联合亚低温康复护理,可以改善凝血功能,减轻神经功能损伤,有利于患者预后,值得临床推广。Objective:To explore effect of Edaravone combined with mild hypothermia rehabilitation nursing on PT,APTT and NIHSS scores in patients with severe craniocerebral injury.Methods:100 patients with severe craniocerebral injury were randomly divided into two groups:the observation group(n=50)and the control group(n=50).The control group was given routine treatment and nursing,and the observation group was given edaravone combined with mild hypothermia rehabilitation nursing.The coagulation function,NIHSS score and prognosis of the two groups were observed.Results:Compared with before nursing,the APTT and PT levels of the two groups increased after nursing(P<0.05),and the observation group was lower than the control group(P<0.05).The NIHSS score of the observation group was lower than that of the control group(P<0.05).The recovery satisfaction of the observation group was higher than that of the control group(P<0.05).Conclusion:Rehabilitation nursing care of Edaravone combined with mild hypothermia can improve the coagulation function of patients with severe craniocerebral injury in neurosurgery,reduce the injury of nerve function,is beneficial to the prognosis of patients,and is worthy of clinical application.

关 键 词：重型颅脑损伤 依达拉奉 亚低温康复护理 凝血功能 NIHSS评分 

分 类 号：R651.1+5[医药卫生—外科学]