补气升阳法对腹泻型肠易激综合征伴失眠患者疗效的影响研究  

Clinical Efficacy of Therapy of Invigorating Qi and Elevating Yang for Treatment of Diarrhea-predominant Irritable Bowel Syndrome Complicated with Insomnia

作　　者：张凤敏 何锦雄 吕沛东 董明国 ZHANG Feng-Min;HE Jin-Xiong;LYU Pei-Dong;DONG Ming-Guo(Dongguan Traditional Chinese Medicine Hospital,Dongguan 523000 Guangdong,China)

机构地区：[1]东莞市中医院,广东东莞523000

出　　处：《广州中医药大学学报》2021年第1期31-35,共5页Journal of Guangzhou University of Traditional Chinese Medicine

摘　　要：【目的】观察补气升阳法治疗阳气虚证腹泻型肠易激综合征(IBS-D)伴失眠患者的临床疗效。【方法】将50例阳气虚证IBS-D伴失眠患者随机分为治疗组和对照组,每组各25例。对照组给予常规西医治疗,治疗组在对照组的基础上加用补气升阳法(补气升阳汤配合艾灸中脘穴和关元穴)治疗,疗程为12周。观察2组患者治疗前后生活质量健康调查简易量表(SF-36)评分、匹兹堡睡眠质量指数(PSQI)评分的变化情况,并评价2组患者的临床疗效。【结果】(1)治疗12周后,治疗组的总有效率为96.0%(24/25),对照组为84.0%(21/25);组间比较,治疗组的总有效率和总体疗效均优于对照组,差异均有统计学意义(P<0.05)。(2)治疗后,2组患者的生活质量SF-36评分均较治疗前明显提高(P<0.05),且治疗组对生活质量SF-36评分的提高作用明显优于对照组,差异有统计学意义(P<0.05)。(3)治疗后,2组患者的PSQI各维度评分及其总分均较治疗前明显降低(P<0.05),且治疗组对PSQI各维度评分及其总分的降低作用均明显优于对照组,差异均有统计学意义(P<0.05)。(4)治疗过程中,2组患者的血、尿、大便常规及肝肾功能等安全性指标均无异常变化。【结论】补气升阳法治疗阳气虚证IBS-D伴失眠患者,疗效确切,可有效改善患者临床症状,提高患者生活质量和睡眠质量。Objective To observe the therapeutic effect of therapy of invigorating qi and elevating yang for the treatment of diarrhea-predominant irritable bowel syndrome(IBS-D)complicated with insomnia. Methods A total of 50 IBS-D patients complicated with insomnia and differentiated as the syndrome of yang-qi deficiency were randomly divided into treatment group and control group,each group having 25 cases. The two groups were given conventional western medicine treatment, and additionally the treatment group was treated with the therapy of invigorating qi and elevating yang by oral use of Buqi Shengyang Decoction combined with moxibustion on the acupoints of Zhongwan(CV12)and Guanyuan(CV4). The course of treatment lasted for 12 weeks. Before and after treatment,the scores of the 36-item short-form health survey(SF-36)and the scores of Pittsburgh sleep quality index(PSQI)in the two groups were observed. And after treatment,the clinical efficacy in the two groups was evaluated. Results(1)After 12 weeks of treatment, the total effective rate in the treatment group was 96.0%(24/25),and that in the control group was 84.0%(21/25). The intergroup comparison showed that the treatment group had higher total effective rate and stronger efficacy than the control group, and the differences were statistically significant(P<0.05).(2)After treatment, the SF-36 scores in the two groups were obviously increased in comparison with those before treatment(P<0.05),and the effect on increasing the SF-36 scores in the treatment group was superior to that in the control group,the difference being statistically significant(P <0.05).(3)After treatment, the dimension scores of PSQI and the overall PSQI scores in the two groups were obviously decreased in comparison with those before treatment(P<0.05),and the effect on decreasing the dimension scores of PSQI and the overall PSQI scores in the treatment group was superior to that in the control group,the difference being statistically significant(P < 0.05).(4)During the trial,the results for the rou

关 键 词：阳气虚证 腹泻型肠易激综合征 失眠 补气升阳汤 艾灸 中脘穴 关元穴 

分 类 号：R259.74[医药卫生—中西医结合]