基于梁直英调肝理肺法治疗支气管哮喘的疗效观察  

Clinical Observation on Treatment of Bronchial Asthma with Therapy of Regulating Liver and Lung Established by LIANG Zhi-Ying

作　　者：张高[1] 廖慧丽[1] 刘建博[1] 黄楚栓 ZHANG Gao;LIAO Hui-Li;LIU Jian-Bo;HUANG Chu-Shuan(The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405 Guangdong,China)

机构地区：[1]广州中医药大学第一附属医院,广东广州510405

出　　处：《广州中医药大学学报》2021年第2期246-249,共4页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：广州市科技计划项目(编号:201803010053)。

摘　　要：【目的】对梁直英教授调肝理肺法治疗支气管哮喘慢性持续期患者的临床疗效进行观察。【方法】采用简单随机法按3︰2比例将60例支气管哮喘慢性持续期患者随机分为治疗组36例和对照组24例。2组患者均给予西医常规治疗,在此基础上,治疗组给予调肝理肺方治疗,疗程为10 d。观察2组患者治疗前后1秒用力呼气容积(FEV1)、第1秒用力呼气容积占预计值的百分比(FEV1%)等肺功能指标的变化情况,评价2组的临床疗效及安全性。【结果】(1)治疗10 d后,治疗组的总有效率为94.4%(34/36),对照组为87.5%(21/24);组间比较(秩和检验),治疗组的疗效优于对照组,差异有统计学意义(P<0.05)。(2)治疗后,2组患者的FEV1、FEV1%等肺功能指标均较治疗前明显改善(P<0.05),且治疗组的改善作用均明显优于对照组,差异均有统计学意义(P<0.05)。(3)治疗期间,治疗组与对照组患者均未出现明显的不良反应。【结论】采用调肝理肺方治疗支气管哮喘慢性持续期患者疗效确切,能有效改善患者临床症状,提高患者肺功能,其疗效优于单纯西医常规治疗。Objective To observe the clinical effect of therapy of regulating liver and lung established by Professor LIANG Zhi-Ying for the treatment of chronic persistent bronchial asthma.Methods A total of 60 chronic persistent bronchial asthma patients were divided into treatment group and control group by simple random method at the proportion of 3∶2.The treatment group had 36 cases,and was treated with the therapy of regulating liver and lung together with the conventional western medicine.The control group had 24 cases,and was treated with conventional western medicine alone.All of the patients in the two groups were treated for 10 days.Before and after treatment,the lung function indicators such as the forced expiratory volume in one second(FEV1)and the percentage of the forced expiratory volume in one second to the predicted volume(FEV1%)in the two groups were recorded.And after treatment,the clinical efficacy and safety in the two groups were also evaluated.Results(1)After treatment for 10 days,the total effective rate in the treatment group was 94.4%(34/36),and that in the control group was 87.5%(21/24).The intergroup comparison showed that the clinical efficacy in the treatment group was stronger than that in the control group,the difference being statistically significant(P<0.05).(2)After the treatment,the lung function indicators of FEV1 and FEV1%in the two groups were much improved in comparison with those before treatment(P<0.05),the observation group had stronger effect on improving the lung function indicators of FEV1 and FEV1%than those in the control group,and the differences were statistically significant(P<0.05).(3)During the trial,no obvious adverse reaction was found in the two groups.Conclusion Therapy of regulating liver and lung combined with conventional western medicine exerts certain effect for the treatment of chronic persistent bronchial asthma through relieving the clinical symptoms and improving the lung function,and its effect is superior to that of the conventional western medicine treat

关 键 词：支气管哮喘 慢性持续期 调肝理肺法 梁直英 疗效观察 

分 类 号：R259.633[医药卫生—中西医结合]