深圳市宝安区散居儿童手足口病危险因素研究  

Risk factors of hand,foot and mouth disease in scattered children in Bao’an District of Shenzhen City

作　　者：邱紫莹 李苑[2] 熊田甜[2] 陈亿雄[2] 彭敬[2] 吴泰顺[2] QIU Zi-ying;LI Yuan;XIONG Tian-tian;CHEN Yi-xiong;PENG Jing;WU Tai-shun(School of Public Health,Sun Yat-sen University,Guangzhou,Guangdong 510080,China;Baoan District Center for Disease Control and Prevention,Shenzhen,Guangdong 518100,China)

机构地区：[1]中山大学公共卫生学院,广东广州510080 [2]深圳市宝安区疾病预防控制中心,广东深圳518100

出　　处：《实用预防医学》2021年第1期62-65,共4页Practical Preventive Medicine

摘　　要：目的探讨宝安区6~36月龄散居儿童手足口病发病的危险因素,提出针对性防控措施。方法采用1∶1匹配病例对照研究方法,病例为自2019年6月1日起上传到《传染病报告信息管理系统》中居住地址位于宝安区内、6~36月龄的手足口病新病例;在同一社区内随机寻找月龄±2个月、同性别、无手足口病/疱疹性咽峡炎/发热伴出疹症状的儿童作为对照。根据自制问卷采用电话访问的形式进行调查。结果共调查病例组和对照组各192人。多因素logistic回归分析显示:和5岁以下儿童一起居住(OR=4.976,P=0.002),发病前10 d接触过手足口病人(OR=2.762,P<0.001),发病前10 d去过游乐场所(OR=5.670,P<0.001),孩子饭前总是/经常吮吸手指(OR=4.879,P=0.010)是危险因素;而看护人喂养前用肥皂洗手频率[总是/经常(OR=0.213,P=0.006)]、孩子饭前总是/经常用肥皂洗手(OR=0.117,P<0.001)是保护因素。结论在宝安区手足口病流行季节公共游乐场所对疾病传播有重要作用,提高看护人和儿童的手卫生、避免儿童接触手足口病患者能降低患病风险,和5岁以下儿童居住的散居儿童家长更应该重视采取预防措施。Objective To explore the risk factors of hand,foot and mouth(HFMD)among scattered children aged 6-36 months in Bao’an District of Shenzhen City,and to put forward the targeted prevention and control measures.Methods We conducted a 1∶1 matched case-control study.The cases were 6-36 months old children with residential address in Bao’an District and newly-diagnosed with HFMD cases that were reported to the Infectious Disease Reporting and Management System since June 1 st,2019.We randomly selected children aged±2 months,same gender,living in the same community and without HFMD/herpangina/fever with rash as controls,and then conducted telephone surveys based on self-made questionnaires.Results We surveyed the case group and the control group(each n=192).Multivariable logistic regression analysis showed that living with children younger than 5 years of age(OR=4.976,P=0.002),having contact with HFMD patients within 10 days before onset of illness(OR=2.762,P<0.001),exposuring to public playground within 10 days before onset of illness(OR=5.670,P<0.001),and always/often sucking fingers(OR=4.879,P=0.010)were the risk factors,while caregivers’frequency of washing hands with soap before meals(always/often(OR=0.213,P=0.006))and children’s hand-washing with soap before meals(always/often OR=0.117,P<0.001)were the protective factors.Conclusions Public playgrounds play important roles for HFMD spreading during epidemic periods in Bao’an District.Improving caregivers’and children’s hand hygiene and avoiding children’s contact with HFMD patients can reduce the risk of illness.More precautions should be taken by parents’scattered children living with children aged below 5 years.

关 键 词：手足口病 配对病例对照研究 危险因素 

分 类 号：R512.5[医药卫生—内科学]