Late-onset non-islet cell tumor hypoglycemia: A case report  

作　　者：Shunichi Matsumoto Eijiro Yamada Yasuyo Nakajima Naoki Yamaguchi Takashi Okamura Toshiki Yajima Satoshi Yoshino Kazuhiko Horiguchi Emi Ishida Masashi Yoshikawa Jun Nagaoka Sho Sekiguchi Mai Sue Shuichi Okada Izumi Fukuda Ken Shirabe Masanobu Yamada 

机构地区：[1]Department of Medicine and Molecular Science,Gunma University Graduate School of Medicine,Maebashi 371-8511,Gunma,Japan [2]Division of General Thoracic Surgery,Integrative Center of General Surgery,Gunma University Hospital,Maebashi 371-8511,Gunma,Japan [3]Department of Endocrinology,Diabetes and Metabolism,Graduate School of Medicine Nippon Medical School,Tokyo 1138602,Japan

出　　处：《World Journal of Clinical Cases》2021年第1期163-169,共7页世界临床病例杂志

摘　　要：BACKGROUND Hypoglycemia due to non-insulin-producing tumors is referred to as non-islet cell tumor hypoglycemia(NICTH).As NICTH is a rare lesion,the natural course of NICTH is not well understood.We report a case of NICTH that was observed 30 years before the onset of hypoglycemia.CASE SUMMARY A 50-year-old man was diagnosed with an abnormal right chest shadow during a routine X-ray examination,but no further examination was undertaken because the lesion appeared benign.Thirty years after the tumor discovery,the patient was admitted to the hospital with symptoms of severe hypoglycemia,which was diagnosed as NICTH based on a complete examination.The tumor was resected and found to be a solitary fibrous mass(15.6 cm×13.7 cm×10.4 cm);thereafter,the patient’s blood glucose levels normalized and he completely recovered.CONCLUSION NICTH can have an acute onset,even if the tumor has been present and asymptomatic over a long time period.

关 键 词：HYPOGLYCEMIA Non-islet cell tumor hypoglycemia Blood glucose Solitary tumor Late onset Case report Insulin-like growth factor II 

分 类 号：R587.3[医药卫生—内分泌]