418例肺癌患者家族癌症发病史流行病学调查分析  

Epidemiological investigation and analysis of the family history of cancer in 418 patients with lung cancer

作　　者：夏银川 张冉[2] 柯晓庆 祝德[1] XIA Yinchuan;ZHANG Ran;KE Xiaoqing;ZHU De(Department of oncology,Bazhong Central Hospital,Bazhong,Sichuan 636000,China;Department of thoracic surgery,Bazhong Central Hospital,Sichuan 636000,China;ICU of Bazhong Central Hospital,Bazhong,Sichuan 636000,China)

机构地区：[1]四川省巴中市中心医院肿瘤科,四川巴中636000 [2]四川省巴中市中心医院胸外科 [3]巴中市中心医院ICU

出　　处：《公共卫生与预防医学》2021年第1期121-124,共4页Journal of Public Health and Preventive Medicine

摘　　要：目的了解肺癌患者中的家族癌症史的流行情况。方法依据《人群疾病家族史和病史调查表》采用面对面的方式对巴中地区418例肺癌患者家族癌症史进行调查。结果418例肺癌患者中家族史癌症阳性和肺癌阳性率分别为36.12%(151/418)和28.47%(119/418),两者间阳性率差异无统计学意义(P>0.05)。患者家属中癌症阳性人群主要为3人或以下,人数越多几率越低(P<0.05)。一级亲属的家族史癌症阳性和肺癌阳性率均显著高于二级和三级亲属(P<0.05)。结论针对性的对癌症患者及其家属进行健康教育尤其是一级亲属的健康教育有助于改善肺癌患者早期诊断。Objective To understand the prevalence of family cancer history among lung cancer patients.Methods The family cancer history of 418 patients with lung cancer was investigated by a face-to-face survey in Bazhong area according to the"Questionnaire on Family History and Medical History of Population Diseases".Results The positive rates of family history of cancer and lung cancer in the 418 patients with lung cancer were 36.12%(151/418)and 28.47%(119/418),respectively.There was no statistical difference in the positive rates between the two(P>0.05).Among the patients′family members,the number of cancer-positive people was mainly 3 or less.The higher the number,the lower the probability(P<0.05).The positive rates of family history of cancer and lung cancer in first-degree relatives were significantly higher than those of second-degree and third-degree relatives(P<0.05).Conclusion Targeted health education for cancer patients and their families,especially health education for first-degree relatives,may help improve the early diagnosis of lung cancer patients.

关 键 词：肺癌 家族史 流行病学 一级亲属 

分 类 号：R181[医药卫生—流行病学]