不同靶浓度丙泊酚复合瑞芬太尼与七氟醚复合瑞芬太尼静吸麻醉用于腹腔镜胆囊切除术的观察  

Observation of Different Target Concentration Propofol Combined with Remifentanil and Sevoflurane Combined with Remifentanil for LC

作　　者：国松[1] 姜万维[1] 郭旭东[1] 秦丹[1] 宋永姣 GUO Song;JIANG Wanwei;GUO Xudong(Zhongshan Hospital, Dalian University, Liaoning Dalian 116001,China)

机构地区：[1]大连大学附属中山医院麻醉科,辽宁大连116001 [2]中国人民解放军联勤保障部队第967医院妇产科,辽宁大连116000

出　　处：《河北医学》2021年第1期33-37,共5页Hebei Medicine

基　　金：大连市医学科学研究计划项目,(编号:1811101)。

摘　　要：目的:研究分析在腹腔镜胆囊切除术(LC)患者中实施不同靶浓度丙泊酚复合瑞芬太尼以及七氟醚复合瑞芬太尼静吸麻醉的效果。方法:选取2019年3月至2019年9月本院腹腔镜切除术的患者共计100例为研究对象,进行前瞻性分析。按随机数字表法分为观察组以及对照组每组50例。对照组接受丙泊酚复合瑞芬太尼麻醉法,观察组接受七氟醚复合瑞芬太尼静吸麻醉。对比两组患者的麻醉效果以及各时间点血流动力学参数情况、不良反应发生情况。结果:观察组在在T1、T2阶段MAP、HR显著高于对照组(P均<0.05),T4、T5阶段MAP、HR显著低于对照组(P均<0.05);观察组T2、T5阶段SpO2显著低于对照组(P均<0.05)。观察组中患者的自主呼吸恢复时间、睁眼时间、言语应答时间、定向力恢复时间均显著短于对照组(P均<0.05)。结论:临床上在LC术中采用七氟醚+瑞芬太尼静吸复合麻醉,可明显维持血流动力学稳定,缩短患者的自主呼吸恢复时间、睁眼时间、言语应答时间、定向力恢复时间,具有良好的临床应用价值。Objective:To investigate the effects of propofol of different target concentrations combined with remifentanil,and sevoflurane combined with remifentanil inhalation anesthesia in patients undergoing laparoscopic cholecystectomy.Methods:A total of 100 patients with laparoscopic resection admitted to our hospital from March 2019 to September 2019 were selected and divided into observation group and control group with random number table,with 50 cases in each group.The control group received propofol combined with remifentanil anesthesia,and the observation group received sevoflurane combined with remifentanil inhalation anesthesia.The effects of anesthesia and hemodynamics parameters and adverse reactions were compared between the two groups.Results:In the observation group,MAP and HR levels in T1 and T2 stagesn were significantly higher than those of the control group(all P<0.05),and MAP and HR levels in T4 and T5 stages were significantly lower than those in the control group(all P<0.05).While at stages T2 and T5,SpO2 of the observation group was significantly lower than that of the control group(all P<0.05).The recovery time of spontaneous breathing,eye opening time,speech response time and directional power recovery time of patients in the observation group were significantly shorter than those in the control group(all P<0.05).Conclusion:Clinical use of sevoflurane remifentanil intravenous anesthesia in LC surgery can significantly maintain hemodynamic stability,shorten the time of spontaneous breathing recovery,eye-opening,speech response and orientation recovery.It has good clinical application value.

关 键 词：腹腔镜胆囊切除术 瑞芬太尼 丙泊酚 七氟醚 

分 类 号：R61[医药卫生—外科学]