胸部低剂量CT检查在住院患者新型冠状病毒肺炎筛查中的应用价值  

The value of low-dose chest CT examination for screening COVID-19 in hospitalized patients

作　　者：潘雪琳[1] 袁元[1] 邓莉萍[1] 程巍[1] 杨帆[1] 赵瑾[1] 李真林[1] 叶倩 PAN Xuelin;YUAN Yuan;DENG Liping;CHENG Wei;YANG Fan;ZHAO Jin;LI Zhenlin;YE Qian(Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China)

机构地区：[1]四川大学华西医院放射科,四川成都610041

出　　处：《西部医学》2021年第1期134-138,共5页Medical Journal of West China

基　　金：四川省科技厅重点研发项目(2019YFS0522);四川大学华西医院学科卓越发展1.3.5工程项目(ZYGD18019)。

摘　　要：目的探讨胸部低剂量CT检查技术在住院患者新型冠状病毒肺炎(COVID-19)筛查中的应用价值。方法纳入2020年2月10日~2020年2月26日来我院行入院前胸部CT排查新冠肺炎的患者216例。采用随机数字表法分为实验组与对照组,每组各108例。实验组采用胸部低剂量CT检查技术,管电压80kV;对照组采用胸部CT检查常规参数,管电压100kV。分别测量、计算并比较两组图像三个层面中肺实质的CT值、图像噪声、肺实质信噪比(SNR)、肺实质-空气对比噪声比(CNR)、主观评分以及辐射剂量指标,包括CT剂量指数(CTDIvol)、剂量长度乘积(DLP)和有效剂量(ED)等。结果两组患者的肺实质CT值、图像噪声、SNR、CNR、主观评分及CTDIvol、DLP、ED之间比较,差异均有统计学意义(P<0.05),且试验组图像噪声高于对照组(P<0.05),SNR、CNR、主观评分、CTDIvol、DLP、ED均低于对照组(P<0.05)。两组的主观评分均高于3分,都能满足诊断要求。结论在住院患者新型冠状病毒肺炎筛查中采用胸部低剂量CT检查,既能满足诊断需求,又能有效降低患者检查过程中所接受的辐射剂量,具有很高的临床应用价值,值得借鉴。Objective To explore the value of low-dose chest CT examination for screening COVID-19 in hospitalized patients.Methods 216 patients underwent chest CT screening for COVID-19 before entering the hospital from February 10 to February 26,2020 were recruited.They were randomly divided into experimental group and control group with 108 cases in each group.In the experimental group,the chest low-dose CT technique was used,and the tube voltage was 80 kV.In the control group,the conventional parameters were examined by chest CT,and the tube voltage was 100 kV.CT value,image noise,SNR,CNR,subjective score and radiation dose index,including CT dose index(CTDIvol),dose length product(DLP)and effective dose(ED),were measured,calculated and compared.Results There were significant differences in CT value,image noise,SNR,CNR,subjective score,CTDIvol,DLP and ED between the two groups(P<0.05).The image noise of the experimental group was higher than that of the control group(P<0.05).The SNR,CNR,subjective score,CTDIvol,DLP,ed of the experimental group were lower than those of the control group(P<0.05).The subjective scores of the two groups were higher than 3,which could meet the diagnostic requirements.Conclusion In COVID-19 patients screening,the low dose CT examination can not only meet the diagnostic needs,but also effectively reduce the radiation dose received by patients during the examination.It has high clinical value and is worth learning from.

关 键 词：胸部CT 低剂量CT 新型冠状病毒肺炎 图像噪声 

分 类 号：R814.42[医药卫生—影像医学与核医学] R519.9[医药卫生—放射医学]