气管及支气管唾液腺型癌外科治疗研究  

Study on the surgical treatment of salivary gland-type carcinoma of trachea and bronchus

作　　者：龙谦[1] 梅宏[1] 孙勇攀[1] 刘迪[1] 许川[1] LONG Qian;MEI Hong;SUN Yongpan;LIU Di;XU Chuan(Department of Thoracic Surgery,Guizhou Provincial People′s Hospital,Guiyang,Guizhou 550002,China)

机构地区：[1]贵州省人民医院胸外科,贵州贵阳550002

出　　处：《现代医药卫生》2021年第2期188-191,共4页Journal of Modern Medicine & Health

基　　金：贵州省科技厅合作计划项目(黔科合作LH字〔2016〕7182)。

摘　　要：目的分析单中心外科治疗原发性气管、支气管唾液腺型癌的临床病理特征及预后。方法收集2008年12月至2019年6月于该科接受手术治疗的42例唾液腺型癌患者的临床资料,并进行随访,分析其临床病理特点及预后影响因素。结果42例唾液腺型癌中黏液表皮样癌(MEC)28例,腺样囊性癌(ACC)14例,无一例上皮-肌皮样癌。相对于MEC,ACC位于气管或主支气管者更多,差异有统计学意义(P<0.05)。随访11~139个月,平均57.2个月。所有患者5年无复发生存率及总体生存率分别为62.6%和76.6%。单因素分析显示,伴淋巴结转移者更易复发且总体生存情况更差(P<0.05);多因素分析显示,伴有纵隔淋巴结转移是患者不良预后的独立影响因素(P<0.05)。结论对于气管、支气管唾液腺型癌,手术切除是首选治疗措施,能取得良好疗效。纵隔淋巴结转移是该类肿瘤不良预后的独立影响因素。Objective To analyze the clinicopathological characteristics and prognosis of primary tracheal and bronchial salivary gland-type carcinoma in single-center surgical treatment.Methods The clinical data of 42 patients with salivary gland cancer who underwent surgical treatment in the department from December 2008 to June 2019 were collected and followed up to analyze their clinicopathological characteristics and prognostic factors.Results Among the 42 cases of salivary gland type carcinoma,28 cases were mucoepidermoid carcinoma(MEC),14 cases were adenoid cystic carcinoma(ACC),and there was no epithelial-myodermal carcinoma.Compared with MEC,there were more cases of ACC located in the trachea or main bronchus,and the difference was statistically significant(P<0.05).The follow-up period was 11 to 139 months,with an average of 57.2 months.The 5-year recurrence-free survival rate and overall survival rate of all patients were 62.6%and 76.6%,respectively.Univariate analysis showed that patients with lymph node metastasis were more likely to relapse and the overall survival was worse(P<0.05);multivariate analysis showed that mediastinal lymph node metastasis was an independent factor for the poor prognosis of patients(P<0.05).Conclusion For tracheal and bronchial salivary gland-type cancer,surgical resection is the first choice for treatment and can achieve good results.Mediastinal lymph node metastasis is an independent factor influencing the poor prognosis of this type of tumor.

关 键 词：唾液腺型癌 气管 支气管 外科手术 治疗 

分 类 号：R655.3[医药卫生—外科学]