聚醚醚酮与钛网治疗去骨瓣减压术后颅骨缺损效果的对比分析  

A comparison of polyetheretherketone and titanimum mesh in therapeutic effect for skull defect after decompressive craniectomy

作　　者：周剑云[1] 张新[1] 高海滨[1] 曹泽[1] 孙炜[1] Zhou Jianyun;Zhangxin;Gao Haibin;Chao Ze;Sun Wei(Department of Neurosurgery,Beijing Boai Hospital,China Rehabilitation Research Centre,College of Rehabilitation,Capital Medical University,Beijing 100068,China)

机构地区：[1]首都医科大学康复医学院中国康复研究中心北京博爱医院神经外科,100068

出　　处：《中国微侵袭神经外科杂志》2021年第1期7-10,共4页Chinese Journal of Minimally Invasive Neurosurgery

摘　　要：目的为比较聚醚醚酮(polyetheretherketone,PEEK)和钛网在去骨瓣减压术后颅骨修补术中的临床应用效果。方法回顾性分析293例颅骨缺损病人的临床资料,其中应用PEEK材料行颅骨修补术58例(PEEK组),应用钛网材料行颅骨修补术235例(钛网组)。比较两组病人塑形效果、术后并发症、手术时间及治疗费用差异。结果两组术后出血、感染、癫癇发生率以及手术出血量差异均无统计学意义(P>0.05),而PEEK组皮下积液发生率、手术时间及手术费用均明显高于钛网组(P<0.05)。钛网组有额部皮肤印迹和外伤后钛网变形的偶发事件。涉及眶部及鼻根的颅骨缺损应用PEEK修补效果良好。结论PEEK、钛网均有良好的生物亲和性,术后并发症少,骨性塑形满意,均可作为颅骨修补术的备选材料。对儿童、青年、女性在经济情况好的情况下,推荐使用PEEK,特别是伴鼻眶缺损者。Objective To compare the clinical outcomes of polyetheretherketone(PEEK)and titanium mesh in cranioplasty after decompressive craniectomy.Methods Clinical data of 293 patients with skull defect were analyzed retrospectively,and 58 patients underwent cranioplasty with PEEK(PEEK group)and 235 with titanium mesh(titanium mesh group).The shaping outcomes,postoperative complications,surgical time and cost were compared between the two groups.Results There was no statistically significant difference in the incidence of complications such as hematoma,infection,seizures and volume of intraoperative bleeding between the PEEK group and the titanium mesh group(P>0.05),while the incidence of postoperative subcutaneous effusion,surgical time and surgical cost were higher in the PEEK group than in the titanium mesh group(P<0.05).There were accidental frontal skin imprinting and deformation of titanium mesh after trauma in the titanium mesh group.For skull defects with orbital and nasal roots,the repair with PEEK achieved a good effect.Conclusions Both PEEK and titanium mesh have good biocompatibility with few postoperative complications and satisfactory bone shaping,thus can be used as alternative materials for cranioplasty.PEEK is recommended for children,young adults and female patients with good economic conditions,especially for those with nasal orbital defects.

关 键 词：颅骨缺损 颅骨修补术 聚醚醚酮 钛网 

分 类 号：R651.15[医药卫生—外科学]