川芎内生菌Fusarium tricinctum的四个新吡喃-2-酮类成分  

Four New 2-Pyrones from Fusarium tricinctum,an Endophytic Fungus of Ligusticum chuanxiong

作　　者：曹钰镁 旷歧轩 巨凤 邓赟[1] 邓放[1] 顾玉诚 任波[1] 郭大乐 Cao Yumei;Kuang Qixuan;Ju Feng;Deng Yun;Deng Fang;Gu Yucheng;Ren Bo;Guo Dale(School of Pharmacy,Chengdu University of Traditional Chinese Medicine,Chengdu 611137;Syngenta Jealott's Hill International Research Centre,Berkshire RG426EY,UK)

机构地区：[1]成都中医药大学药学院,成都611137 [2]Syngenta Jealott's Hill International Research Centre,Berkshire RG426EY,UK

出　　处：《有机化学》2020年第12期4328-4331,共4页Chinese Journal of Organic Chemistry

基　　金：Project supported by the National Natural Science Foundation of China(No.81973460);the Foundation of Science and Technology Department of Sichuan Province(No.2018JY0186);the Xinglin Scholar Research Promotion Project of Chengdu University of Traditional Chinese Medicine(No.BSH2018008)。

摘　　要：采用硅胶、凝胶等柱色谱及反相碳十八制备液相色谱及手性拆分从川芎内生菌Fusariumtricinctum的糙米培养基中分离得到四个具有相同平面结构的2-吡喃酮类化合物,并采用改良的Snatzke法对其绝对构型进行鉴定.By silica gel,Sephadex LH-20 column chromatography as well as preparative high performance liquid chromatography(HPLC),four previously undescribedα-pyrones sharing same primary structure were isolated from the brown rice solid medium of Fusarium tricinctum.Their structures were elucidated by spectroscopic analyses and their absolute configurations were finally confirmed by a modified Snatzke’s method.

关 键 词：2-吡喃酮 Fusarium tricinctum 川芎 诱导圆二色谱 

分 类 号：O626[理学—有机化学]