Frequency and distribution of neglected tropical diseases in Mozambique:a systematic review  

作　　者：Berta Grau-Pujol Marilia Massangaie Jorge Cano Carmen Maroto Alcino Ndeve Francisco Saute Jose Munoz 

机构地区：[1]ISGIobal,Hospital Clinic,Universitat de Barcelona,Barcelona,Spain [2]Centro de Investigagao em Saude da Manhiga(CISM),Maputo,Mozambique [3]Mundo Sano Foundation,Buenos Aires,Argentina [4]Direcgao Nacional de Saude Publica,Ministerio da Saude,Maputo,Mozambique [5]Faculty of Infectious and Tropical Diseases,London School of Hygiene and Tropical Medicine,London,UK [6]Liverpool School of Tropical Medicine,Liverpool,UK [7]No Leprosy Remains,Maputo,Mozambique

出　　处：《Infectious Diseases of Poverty》2019年第6期1-11,共11页贫困所致传染病（英文）

基　　金：ISGIobal is a mem ber of the CERCA Programme,Generalitat de Catalunya.CISM is supported by the Governm ent of Mozambique and the Spanish Agency for International Developm ent(AECID);BG received financial support for this study from Mundo Sano Foundation(www.mundosano.org).The funders had no role in study design,data collection,analysis,interpretation of data,decision to publish,or preparation of the manuscript.

摘　　要：Background:Neglected tropical diseases(NTDs)affect more than one billion people living in vulnerable conditions.In spite of initiatives recently contributing to fill NTDs gaps on national and local prevalence and distribution,more epidemiological data are still needed for effective control and elimination interventions.Main text:Mozambique is considered one of the countries with highest NTDs burden although available data is scarce.This study aims to conduct a systematic review on published available data about the burden and distribution of the different NTDs across Mozambique since January 1950 until December 2018.We identified manuscripts from electronic databases(Pubmed,EmBase and Global Health)and paper publications and grey literature from Mozambique Ministry of Health.Manuscripts fulfilling inclusion criteria were:crosssectional studies,ecological studies,cohorts,reports,systematic reviews,and narrative reviews capturing epidemiological information of endemic NTDs in Mozambique.Case-control studies,letters to editor,case reports and case series of imported cases were excluded.A total of 466 manuscripts were initially identified and 98 were finally included after the revision following PRISMA guidelines.Eleven NTDs were reported in Mozambique during the study span.Northern provinces(Nampula,Cabo Delgado,Niassa,Tete and Zambezia)and Maputo province had the higher number of NTDs detected.Every disease had their own report profile:while schistosomiasis have been continuously reported since 1952 until nowadays,onchocerciasis and cysticercosis last available data is from 2007 and Echinococcosis have never been evaluated in the country.Thus,both space and time gaps on NTDs epidemiology have been identified.Conclusions:This review assembles NTDs burden and distribution in Mozambique.Thus,contributes to the understanding of NTDs epidemiology in Mozambique and highlights knowledge gaps.Hence,the study provides key elements to progress towards the control and interruption of transmission of these diseases in the coun

关 键 词：Neglected tropical diseases Mozambique Africa EPIDEMIOLOGY POVERTY Infectious diseases Review HELMINTH TRACHOMA LEPROSY 

分 类 号：R71[医药卫生—妇产科学]