Pay-it-forward gonorrhea and chlamydia testing among men who have sex with men in China:a study protocol for a three-arm cluster randomized controlled trial  

作　　者：Tiange P.Zhang Fan Yang Weiming Tang Marcus Alexander Laura Forastiere Navin Kumar Katherine Li Fei Zou Ligang Yang Guodong Mi Yehua Wang Wenting Huang Amy Lee Weizan Zhu Peter Vickerman Dan Wu Bin Yang Nicholas A.Christakis Joseph D.Tucker 

机构地区：[1]University of North Carolina at Chapel Hill Project-China,No.2 Lujing Road,Guangzhou 510095,China [2]Loyola University Chicago Stritch School of Medicine,Maywood,IL,USA [3]School of Medicine,University of North Carolina at Chapel Hill,Chapel Hill,North Carolina,USA [4]Southern Medical University Dermatology Hospital,Guangzhou,China [5]Human Nature Lab,Department of Sociology,Yale University,New Haven,CT,USA [6]Weill Cornell Medical College,New York,NY,USA [7]Department of Biostatistics,University of North Carolina at Chapel Hill,Chapel Hill,North Carolina,USA [8]Blued,Beijing,China [9]Zhitong Guangzhou LGBT Center,Guangzhou,China [10]School of Social and Community Medicine,University of Bristol,Bristol,UK [11]Faculty of Infectious and Tropical Diseases,London School of Hygiene and Tropical Medicine,London,UK

出　　处：《Infectious Diseases of Poverty》2019年第4期85-95,共11页贫困所致传染病（英文）

基　　金：the National Key Research and Development Program of China(2017YFE0103800);the National Institutes of Health NIAID NIAID K24AI143471,1UG3HD096929-01,NIA P30(P30AG034420);UNC-South China STD Research Training Center(FIC 1D43TW009532-01);UNC Center for AIDS Research(NIAID 5P30AI050410);Doris Duke Charitable Foundation(International Clinical Research Fellowship to TZ);SESH(Social Entrepreneurship to Spur Health)Global.

摘　　要：Background:Gonorrhea and chlamydia testing rates are poor among Chinese men who have sex with men(MSM).A quasi-experimental study suggested that a pay-it-forward strategy increased dual gonorrhea/chlamydia testing among MSM.Pay-it-forward offers an individual a gift(e.g.,a free test)and then asks the same person if they would like to give a gift to another person.This article reports the protocol of a randomized controlled trial to evaluate dual gonorrhea/chlamydia test uptake and other outcomes among MSM in three arms-a pay-it-forward arm,a pay-what-you-want arm,and a standard of care arm.Methods:Three hundred MSM will be recruited at three HIV testing sites in Guangzhou and Beijing.Testing sites include two hospital-based MSM sexually transmitted diseases clinics and one MSM community-based organization.Eligible participants will be born biologically male,aged 16 years or older,reporting previous anal sex with another man,having never participated in the pay-it-forward program,without previous gonorrhea and chlamydia testing in the past 12 months,and residing in China.Following a cluster randomized design,every cluster of ten participants will be randomly allocated into one of three arms:(1)a pay-it-forward arm in which men are offered free gonorrhea and chlamydia testing and then asked whether they would like to donate("pay it forward")toward testing for future testers;(2)a pay-what-you-want arm in which men are offered free testing and told to decide how much to pay after receiving the test;(3)a standard of care arm in which men can pay the full price for dual gonorrhoea and chlamydia testing.The primary outcome is dual gonorrhoea/chlamydia testing as verified by administrative records.Secondary outcomes include incremental cost per test,incremental cost per diagnosis,community connectedness,and social cohesion.Primary outcome will be calculated for each arm using intention-to-treat and compared using one-sided 95%confidence intervals with a margin of 20%increase defined as superiority.Discussion:This study w

关 键 词：Men who have sex with men Gonorrhoea and chlamydia testing Pay-it-forward Integrated HIV testing China Randomized controlled trial 

分 类 号：R51[医药卫生—内科学]