Long-term outcomes of patients following retrograde chronic total occlusion intervention with Guidezilla reverse controlled antegrade and retrograde tracking(“Guidezilla reverse CART”)technique  

作　　者：WU Kai-ze LUO Bing-zheng HUANG Ze-han ZHONG Zhi-an LIAO Hong-tao ZHANG Bin 吴开泽;骆炳政;黄泽涵;钟志安;廖洪涛;张斌(Department of Cardiovascular Medicine, Affiliated Nanhai Hospital, Southern Medical University (People's Hospital of Nanhai District);The Second School of Clinical Medicine, Southern Medical University, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences;Department of Cardiovascular Medicine, The Second Affiliated Hospital of Guangzhou Medical University;Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People ' s Hospital, Guangdong Academy of Medical Sciences)

机构地区：[1]Department of Cardiovascular Medicine,Affiliated Nanhai Hospital,Southern Medical University(People's Hospital of Nanhai District),Foshan 528200,China [2]The Second School of Clinical Medicine,Southern Medical University,Guangdong Provincial People's Hospital,Guangdong Academy of Medical Sciences,Guangzhou 510100,China [3]Department of Cardiovascular Medicine.The Second Affiliated Hospital of Guangzhou Medical University,Guangzhou 510100,China [4]Department of Cardiology,Guangdong Cardiovascular Institute,Guangdong Provincial People's Hospital,Guangdong Academy of Medical Sciences,Guangzhou 510100,China

出　　处：《South China Journal of Cardiology》2020年第4期247-255,303,共10页岭南心血管病杂志（英文版）

基　　金：supported by Science and Technology Planning Project of Guangdong Province(No.2016A020216022)。

摘　　要：Background The Guidezilla reverse controlled antegrade and retrograde tracking("Guidezilla reverse CART")technique has become one of guidewire crossing techniques in current retrograde coronary total occlusion(CTO)percutaneous coronary intervention(PCI),but has received limited study regarding long-term outcomes.Our aim is to investigate procedural and long-term outcomes in a real-world cohort of CTO patients who underwent retrograde PCI with the"Guidezilla reverse CART"technique.Methods Our study included 315 patients who underwent retrograde CTO PCI,with 86 patients treated with"Guidezilla reverse CART"technique(the Guidezilla group)at Guangdong Cardiovascular Institute from January 2015 to December 2017.The median follow-up was 1.9 years.Major adverse cardiac events(MACE)were analyzed using the Kaplan-Meier method,and independent predictors of long-term MACE were determined using a multivariable Cox model.Results Procedural success of the Guidezilla group and non-Guidezilla group were 95.3%and 82.1%,respectively(P=0.003).The procedural complications and in-hospital MACE were similar between both groups.During the 4-year follow-up,27 patients had MACE.Multivariable analysis revealed that the"Guidezilla reverse CART"technique was not associated with worse long-term clinical outcomes[hazard ratio(HR):2.11;95%CI:0.64-6.98,P=0.220].Conclusions The"Guidezilla reverse CART"technique improves the success rate in retrograde PCI of more complex CTOs and is associated with similar complication and in-hospital MACE rates.The"Guidezilla reverse CART"technique is not significantly associated with adverse clinical outcomes.

关 键 词：extension catheter Guidezilla chronic total occlusion percutaneous coronary intervention RETROGRADE major adverse cardiac events 

分 类 号：R541.4[医药卫生—心血管疾病]