Surveillance-based evidence:elimination of schistosomiasis as a public health problem in the Peoples’Republic of China  

作　　者：Jing Xu Shi-Zhu Li Li-Juan Zhang Robert Bergquist Hui Dang Qiang Wang Shan Lv Tian-Ping Wang Dan-Dan Lin Jian-Bing Liu Guang-Hui Ren Kun Yang Yang Liu Yi Dong Shi-Qing Zhang Xiao-Nong Zhou 

机构地区：[1]National Institute of Parasitic Diseases,Chinese Center for Disease Control and Prevention,WHO Collaborating Centre for Tropical Diseases,Chinese Center for Tropical Disease Research,Shanghai 200025,People’s Republic of China [2]Geospatial Health,Ingerod 407,S-45494 Brastad,Sweden [3]Anhui Provincial Institute of Schistosomiasis Control,Hefei,Anhui Province 230061,People’s Republic of China [4]Jiangxi Provincial Institute of Parasitic Disease,Nanchang,Jiangxi Province 330006,People’s Republic of China [5]Hubei Provincial Institute of Schistosomiasis Control,Hubei Center for Disease Control,Wuhan,Hubei Province 430079,People’s Republic of China [6]Hunan Provincial Institute of Schistosomiasis Control,Yueyang,Hunan Province 414000,People’s Republic of China [7]Jiangsu Provincial Institute of Schistosomiasis Control,Wuxi,Jiangsu Province 214064,People’s Republic of China [8]Sichuan Center for Disease Control,Chengdu,Sichuan Province 610041,People’s Republic of China [9]Yunnan Provincial Institute of Endemic Diseases Control and Prevention,Dali,Yunnan Province 671000,People’s Republic of China

出　　处：《Infectious Diseases of Poverty》2020年第3期39-50,共12页贫困所致传染病（英文）

基　　金：This study was financially supported by the Natural Science Foundation of China(No.30590373);the National Special Science and Technology Project for Major Infectious Diseases of China(No.2012ZX10004–220,2016YFC1202000).

摘　　要：Background:A steady progress on schistosomiasis control in the Peoples’Republic of China(P.R.China)was achieved and broadened into the twelve-year medium and long term national plan(MLNP)which marled the implementation of an integrated control strategy across all endemic areas in P.R.China in 2004.To understand the endemic trends of schistosomiasis to assess the effectiveness of an integrated strategy,we conducted an analysis of schistosomiasis surveillance data spanned from 2005 to 2015.Methods:The schistosomiasis sentinel surveillance data from sentinel sites were collected and analyzed from 2005 to 2015.In these sentinel sites,residents aged 6 years or above were screened annually by indirect hemagglutination assay(IHA),while only antibody positives were followed by stool examination either Kato-katz method(KK)and/or hatching technique(HT).Domestic animals raised in sentinel sites were examined by HT for confirming the infection of schistosomes.Snail investigation was conducted each year through systematic sampling method combined with environmental sampling method.The snails collected from field were tested by microscopic dissection method.The infection rates of schistosomes in residents,domestic animals and snails,as well as the indicators reflecting the snails’distribution were calculated and analyzed.ANOVA analysis was used to examine the changes of the number of eggs per gram feces in population and Chi-square test was used to examine any change in proportions among groups.Results:A total of 148902 residents from sentinel sites attended this study and 631676 blood samples were examined by IHA test during the 11 covered years.The annual average antibody positive rates presented a significant decrease trends,from 17.48%(95%CI:17.20–17.75%)in 2005 to 5.93%(95%CI:5.71–6.15%)(χ2=8890.47,P<0.001)in 2015.During 2005–2015,the average infection rate of schistosomes in residents declined from 2.07%(95%CI:1.96–2.17%)to 0.13%(95%CI:0.09–0.16%),accompanied by significant decrease of infection intensity

关 键 词：SCHISTOSOMIASIS SURVEILLANCE Infection rate ELIMINATION China 

分 类 号：R532.21[医药卫生—内科学]