密闭流动池脉冲流动液流速的电阻抗参数表征方法研究  

A study on the characterization method of PEL’s velocity in the closed flow cell based on electrical impedance parameters

作　　者：马结实 周德强 张和华 颜乐先 种银保 MA Jieshi;ZHOU Deqiang;ZHANG Hehua;YAN Lexian;Chong Yinbao(Daping Hospital,Army Medical University,Chongqing,400042,China;The Second Affiliated Hospital,Army Medical University,Chongqing,400037,China)

机构地区：[1]陆军军医大学大坪医院,重庆400042 [2]陆军军医大学第二附属医院,重庆400037

出　　处：《中国医学物理学杂志》2021年第1期93-98,共6页Chinese Journal of Medical Physics

基　　金：陆军特色医学中心人才创新能力培养计划项目(2019CXJSC021)。

摘　　要：目的:利用流过输血输液装置密闭流动池的脉冲流动液的电阻抗参数表征流动液的流速。方法:应用精密阻抗分析仪测量该装置5个档位输液速率下的密闭流动池脉冲流动液的电阻抗模值的波形;对获得的电阻抗波形进行频谱分析,计算出各个电阻抗波形频谱主频,统计分析各个流速对应主频的差异;通过相关性分析和曲线估计确定脉冲流动液流速和其电阻抗波形频谱主频之间的回归关系。结果:直观测量和统计分析均表明脉冲流动液的电阻抗波形的变化频率随其流速的增加而升高(P<0.05);脉冲流动液流速与其电阻抗波形频谱主频具有相关性(r=0.99,P<0.05),两者符合二项式关系y=-0.0012x^2+0.1769x-0.134,R^2=0.9998。结论:可以用密闭流动池脉冲流动液的电阻抗参数表征其流速。Objective To characterize the velocity of pulse flowing liquid(PFL)with electrical impedance parameters of PFL flowing in the closed flow cell(CFC).Methods The waveforms of the FPL’s electrical impedance moduli in a CFC were measured by a sophisticated impedance analyzer at five levels of infusion rate.The obtained electrical impedance waveforms were subjected to spectrum analysis,and the dominant frequency of the spectrum of each electrical impedance waveforms was calculated.The difference of each dominant frequency was analyzed corresponding to the five flow rates.The correlation between the PFL’s velocity and its corresponding dominant frequency in spectrum of the electrical impedance waveforms was determined by the correlation analysis and curve estimation.Results Both the visual determination and the statistical analysis indicated that the dominant frequency of the PFL in the spectrum of electrical impedance waveforms increases with the increase of its flow velocity(P<0.05).The velocity of the PFL was correlated well with the dominant frequency in spectrums of the electrical impedance waveforms(r=0.99,P<0.05).The two were in a binomial relationship:y=-0.0012 x^2+0.1769 x-0.134,R^2=0.9998.Conclusion The velocity of PFL through the CFC could be characterized by the electrical impedance parameter of the PFL.

关 键 词：失血性休克 电阻抗 脉冲流动液 流速 频谱分析 

分 类 号：R318[医药卫生—生物医学工程]