红参的化学成分及药理作用研究进展  

Research progress on chemical constituents and pharmacological activities of Ginseng Radix et Rhizoma Rubra

作　　者：樊伟旭 詹志来 侯芳洁[1] 郑玉光[1,3] FAN Wei-xu;ZHAN Zhi-lai;HOU Fang-jie;ZHENG Yu-guang(Hebei University of Chinese Medicine,Traditional Chinese Medicine Processing Technology Innovation Center of Hebei Province,Shijiazhuang 050000,China;State Key Laboratory of Dao-di Herbs breeding base,National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China;Hebei Chemical & Pharmaceutical College,Shijiazhuang 050026,China)

机构地区：[1]河北中医学院河北省中药炮制技术创新中心,石家庄050000 [2]中国中医科学院中药资源中心道地药材国家重点实验室培育基地,北京100700 [3]河北化工医药职业技术学院,石家庄050026

出　　处：《天然产物研究与开发》2021年第1期137-149,共13页Natural Product Research and Development

基　　金：中央本级重大增减支项目-名贵中药资源可持续利用能力建设(2060302);孙宝惠全国名老中医药专家传承工作室项目(7002016008005);河北省二期现代农业产业技术体系创新团队项目(HBCT2018060205)。

摘　　要：红参为人参常用炮制品之一,其化学成分主要有皂苷类、挥发油类、糖类、氨基酸类、微量元素等;药理作用研究发现红参主要具有增强免疫、抗肿瘤、抗氧化、抗衰老、抗疲劳、抗糖尿病、抗肝肾毒性作用等。红参在加工过程中会产生多种成分,如人参皂苷Rg3、人参皂苷Rh1、人参皂苷Rh2、人参炔醇、精氨酸双糖苷、麦芽酚等,这会使得红参的某些药理作用增强。本文则系统整理了2010~2020年红参的化学成分及药理活性的研究进展,以期为红参的质量控制、临床应用提供理论依据。Ginseng Radix et Rhizoma Rubra(GRRR)is one of the well-known medical materials which are made from ginseng through the Chinese traditional Medicine processing methods.Its chemical components mainly include saponins,volatile oils,sugars,amino acids,trace elements and so on.Pharmacological research activities have showed that GRRR has positive effects in enhancing immune system,anti-tumor,anti-oxidation,anti-aging,anti-fatigue,anti-diabetes,anti-hepatorenal toxicity,etc.Many components can be produced during processing,for example,ginsenosides Rg3,Rh1,Rh0,panaxynol,arginyl-fructosyl-glucose,maltol,which could help strengthen the pharmacological activities of GRRR.This article,while systematizing the research progress of the chemical composition and pharmacological researches on GRRR during 2010 and 2020,is aimed to provide a theoretical basis for quality control and clinical application of GRRR.

关 键 词：红参 化学成分 药理作用 研究进展 

分 类 号：R284.1[医药卫生—中药学] R285[医药卫生—中医学]