采用顶空-气相色谱-离子迁移谱分析加工前后浙麦冬中的挥发性有机物  

Analysis of VOCs in zhemaidong before and after processing by headspace-gas chromatography-ion migration spectrum

作　　者：何佳 叶丽华 李静慧 鲁梦霞 张文婷 He Jia;Ye Lihua;Li Jinghui;Lu Mengxia;Zhang Wenting(College of Pharmaceutical Sciences,Zhejiang Chinese Medical Unversity,Hangzhou 310053,China;Zhengda Qingchunbao Pharmaceutical Limited Company,Hangzhou 310023,China;Zhejiang Institute for Food and Drug Control,Hangzhou 310052,China;State Drug Administration Key Laboratory for Quality Evaluation of Proprietary Chinese Medicines,Hangzhou 310052,China)

机构地区：[1]浙江中医药大学药学院,杭州310053 [2]正大青春宝药业有限公司,杭州310023 [3]浙江省食品药品检验研究院,杭州310052 [4]国家药品监督管理局中成药质量评价重点实验室,杭州310052

出　　处：《分析仪器》2021年第1期103-108,共6页Analytical Instrumentation

基　　金：国家中医药管理局支撑计划(ZYBZH-C-ZJ-60)。

摘　　要：目的:研究浙麦冬加工前后其挥发性有机物的变化。方法:采用顶空-气相色谱-离子迁移(HS-GC-IMS)法对浙麦冬药材及其加工后的饮品中的挥发性有机物进行分离鉴定。采用主成分分析法(PCA)对加工前后的浙麦冬样品进行分类。结果:共分离得到挥发性有机物53个,其中41个物质得到了鉴定。主成分分析结果显示浙麦冬药材与加工后的浙麦冬饮片可明显聚为两类。表明浙麦冬加工前后其挥发性有机物发生了较大的变化。Headspace-gas chromatography-ion mobility spectrometry(HS-GC-IMS)method was used to separate and identify the volatile organic compounds(VOCs)in medicinal materials of Zhemaidong and its processed drinks.The samples were classified by principal component analysis(PCA)before and after processing.A total of 53 VOCs were isolated,and 41 of them were identified.The results of principal component analysis showed that Zhemaidong before and after processing could be divided into two groups.The results showed that the VOCs changed greatly before and after Zhemaidong processing.

关 键 词：顶空-气相色谱-离子迁移谱 浙麦冬 加工 挥发性有机物 

分 类 号：O652[理学—分析化学] R284.1[理学—化学]