Metabolic engineering for the microbial production of isoprenoids:Carotenoids and isoprenoid-based biofuels  

作　　者：Fu-Xing Niu Qian Lu Yi-Fan Bu Jian-Zhong Liu 

机构地区：[1]Biotechnology Research Center and Biomedical Center,School of Life Sciences,Sun Yat-sen University,Guangzhou 510275,China [2]South China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center,School of Life Sciences,Sun Yat-sen University,Guangzhou 510275,China

出　　处：《Synthetic and Systems Biotechnology》2017年第3期167-175,共9页合成和系统生物技术（英文）

基　　金：the National Natural Science Foundation of China(Grant NO.21276289);the Natural Science Foundation of Guangdong Province(NO.2015A030311036);the Project of the Scientific and Technical Program of Guangdong Province(NO.2015A010107004);the Project of the Scientific and Technical Program of Guangzhou(NO.201607010028)for their financial support.

摘　　要：Isoprenoids are the most abundant and highly diverse group of natural products.Many isoprenoids have been used for pharmaceuticals,nutraceuticals,flavors,cosmetics,food additives and biofuels.Carotenoids and isoprenoid-based biofuels are two classes of important isoprenoids.These isoprenoids have been produced microbially through metabolic engineering and synthetic biology efforts.Herein,we briefly review the engineered biosynthetic pathways in well-characterized microbial systems for the production of carotenoids and several isoprenoid-based biofuels.

关 键 词：Carotenoids Isoprenoid-based biofuel Metabolic engineering Synthetic biology 

分 类 号：F42[经济管理—产业经济]