Manufacturing of graded titanium scaffolds using a novel space holder technique  

作　　者：Yunhui Chen Damon Kent Michael Bermingham Ali Dehghan-Manshadi Gui Wang Cuie Wen Matthew Dargusch 

机构地区：[1]Queensland Centre for Advanced Materials Processing and Manufacturing(AMPAM),The University of Queensland,St.Lucia,4072,Australia [2]School of Science and Engineering,University of the Sunshine Coast,Maroochydore DC,QLD,4558,Australia [3]ARC Research Hub for Advanced Manufacturing of Medical Devices,Australia [4]School of Engineering,RMIT University,Melbourne,3001,Australia

出　　处：《Bioactive Materials》2017年第4期248-252,共5页生物活性材料（英文）

基　　金：the support of the ARC Research Hub for Advanced Manufacturing of Medical Devices(IH150100024);M.J.Bermingham acknowledges the support of the ARC Discovery Early Career Researcher Awards(DE160100260).

摘　　要：To optimize both the mechanical and biological properties of titanium for biomedical implants,a highly flexible powder metallurgy approach is proposed to generate porous scaffolds with graded porosities and pore sizes.Sugar pellets acting as space holders were compacted with titanium powder and then removed by dissolution in water before sintering.The morphology,pore structure,porosity and pore interconnectivity were observed by optical microscopy and SEM.The results show that the porous titanium has porosity levels and pore size gradients consistent with their design with gradual and smooth transitions at the interfaces between regions of differing porosities and/or pore sizes.Meanwhile,the porous titanium has high interconnectivity between pores and highly spherical pore shapes.In this article we show that this powder metallurgy processing technique,employing the novel sugar pellets as space-holders,can generate porous titanium foams with well-controlled graded porosities and pore sizes.This method has excellent potential for producing porous titanium structures for hard tissue engineering applications.

关 键 词：Porous scaffolds TITANIUM Powder metallurgy Space holder Graded porosity 

分 类 号：TG1[金属学及工艺—金属学]