Recyclable magnetite-silver heterodimer nanocomposites with durable antibacterial performance  

作　　者：Chunyan Yong Xiaoqin Chen Qian Xiang Qiang Li Xiaodong Xing 

机构地区：[1]College of Chemical Engineering,Nanjing University of Science and Technology,Nanjing 210094,China

出　　处：《Bioactive Materials》2018年第1期80-86,共7页生物活性材料（英文）

基　　金：This research was supported by the funding from the National Natural Science Foundation of China(No.81460107).

摘　　要：There is a significant need for magnetite-silver nanocomposites that exhibit durable and recyclable antimicrobial activity.In this study,magnetic iron oxide nanoparticles(Fe3O4 NPs)coated with ethylenediamine-modified chitosan/polyacrylic acid copolymeric layer(Fe3O4@ECS/PAA)were fabricated.Subsequently,directly deposited silver(Ag)NPs procedure was carried out to form the antibacterial heterodimers of Fe3O4@ECS/PAA-Ag NPs.The composition and morphology of the resultant nanostructures were confirmed by FT-IR,XRD,TEM and TGA.The overall length of the heterodimers was approximately 45 nm,in which the mean diameter of Fe3O4@ECS/PAA NPs reached up to 35 nm,and that of Ag NPs was around 15 nm.The mass fraction of silver NPs in the nanocomposites was about 63.1%.The obtained Fe3O4@ECS/PAA NPs exhibited good colloidal stability,and excellent response to additional magnetic field,making the NPs easy to recover after antibacterial tests.In particular,the Fe3O4@ECS/PAAAg NPs retained nearly 100%biocidal efficiency(106e107 CFU/mg nanoparticles)for both Gram-negative bacteria E.coli and Gram-positive bacteria S.aureus throughout ten cycles without washing with any solvents or water,exhibiting potent and durable antibacterial activity.

关 键 词：Heterodimeric nanostructure ANTIBACTERIAL Chitosan coating Silver nanoparticle RECYCLABLE 

分 类 号：O63[理学—高分子化学]