药线点灸联合西医综合治疗瘀热互结型急性胰腺炎疗效观察  

Efficacy Observation of Medicated Thread Moxibustion and Comprehensive Western Medicine for Acute Pancreatitis due to Binding of Stasis and Heat

作　　者：李生发[1] 刘熙荣[1] 周衡[1] 林华胜[1] 张夏[1] 牟丽环[1] LI Sheng-fa;LIU Xi-rong;ZHOU Heng;LIN Hua-sheng;ZHANG Xia;MOU Li-huan(Xianhu Branch of the First Affiliated Hospital of Guangxi University of Chinese Medicine,Nanning 530001,China)

机构地区：[1]广西中医药大学第一附属医院仙葫院区,南宁530001

出　　处：《上海针灸杂志》2021年第2期168-173,共6页Shanghai Journal of Acupuncture and Moxibustion

基　　金：广西中西医药民族医药自筹经费科研课题(GZZC16-02)。

摘　　要：目的观察壮医药线点灸联合西医综合治疗瘀热互结型急性胰腺炎患者的临床疗效。方法将60例瘀热互结型急性胰腺炎患者根据随机数字表法分为观察组和对照组,每组30例。观察组采用壮医药线点灸联合西医综合治疗,对照组仅接受西医综合治疗。两组均治疗10 d,观察两组临床疗效,记录患者治疗期间不良反应发生情况。分别于入院当天和治疗结束时采集患者外周静脉血5 mL,检测并比较两组血超敏C反应蛋白(hs-CRP)、血/尿淀粉酶、肿瘤坏死因子-α(TNF-α)、白细胞介素(IL)-6和IL-10水平;检测并比较两组患者治疗前后的尿淀粉酶水平变化情况。结果治疗后观察组总有效率高于对照组,差异有统计学意义(P<0.05);观察组患者腹痛消失时间、血/尿淀粉酶恢复时间、住院时间均短于对照组,差异均有统计学意义(P<0.05)。两组患者治疗后血/尿淀粉酶水平均较治疗前降低(P<0.05),且观察组均低于对照组,差异均有统计学意义(P<0.05);两组患者治疗后hs-CRP、IL-6、TNF-α水平均较治疗前降低(P<0.05),而IL-10水平均较治疗前升高(P<0.05),且观察组治疗后hs-CRP、IL-6、TNF-α水平均低于对照组,IL-10水平高于对照组,差异均有统计学意义(P<0.05)。治疗期间两组均无不良反应发生。结论壮医药线点灸联合西医综合治疗瘀热互结型急性胰腺炎可更好更快地缓解患者各主要症状体征,促进血/尿淀粉酶快速恢复,减轻患者相关炎症反应,且无不良反应发生。Objective To observe the clinical efficacy of medicated thread moxibustion of Zhuang medicine plus comprehensive Western medicine in treating acute pancreatitis due to binding of stasis and heat.Method Sixty patients with acute pancreatitis due to binding of stasis and heat were divided into an observation group and a control group using the random number table method,with 30 cases in each group.The observation group was treated with medicated thread moxibustion of Zhuang medicine plus comprehensive Western medicine treatment,and the control group only received the comprehensive Western medicine treatment.The two groups were treated for 10 d.The clinical efficacy was observed and the adverse reactions that occurred during treatment were recorded in each group.At admission and the end of treatment,5 mL peripheral venous blood was collected to detect the levels of high-sensitivity C-reactive protein(hs-CRP),serumd/urine amylase,tumor necrosis factor(TNF)-α,interleukin(IL)-6 and IL-10;the level of urine amylase was determined before and after treatment in the two groups.Result After treatment,the total effective rate was higher in the observation group than in the control group,and the difference was statistically significant(P<0.05);the abdominal pain duration,serum/urine amylase recovery time and hospitalization duration were shorter in the observation group than in the control group,and the differences were statistically significant(P<0.05).The serum/urine amylase level declined after treatment in both groups(P<0.05),and was lower in the observation group than in the control group,with statistical significance(P<0.05);the levels of hs-CRP,IL-6 and TNF-αdropped(P<0.05)and the level of IL-10 increased(P<0.05)after treatment in both groups,and the levels of hs-CRP,IL-6 and TNF-αwere lower and the level of IL-10 was higher in the observation group than in the control group,all with statistical significance(P<0.05).No adverse reactions occurred during treatment in the two groups.Conclusion Medicated thread moxibust

关 键 词：灸法 线壮灸 胰腺炎 腹痛 淀粉酶 肿瘤坏死因子-α 白细胞介素-6 

分 类 号：R246.1[医药卫生—针灸推拿学]