Photo-controlled degradation of PLGA/Ti3C2 hybrid coating on Mg-Sr alloy using near infrared light  

作　　者：Li Liu Bo Huang Xiangmei Liu Wei Yuan Yufeng Zheng Zhaoyang Li Kelvin Wai Kwok Yeung Shengli Zhu Yanqin Liang Zhenduo Cui Shuilin Wu 

机构地区：[1]Hubei Key Laboratory of Polymer Materials,Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials,School of Materials Science&Engineering,Hubei University,Wuhan,430062,China [2]State Key Laboratory for Turbulence and Complex System and Department of Materials Science and Engineering,College of Engineering,Peking University,Beijing,100871,China [3]The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China,School of Materials Science&Engineering,Tianjin University,Tianjin,300072,China [4]Department of Orthopaedics&Traumatology,Li Ka Shing Faculty of Medicine,The University of Hong Kong,Pokfulam,Hong Kong,999077,China

出　　处：《Bioactive Materials》2021年第2期568-578,共11页生物活性材料（英文）

基　　金：This study was jointly supported by the Natural Science Fund of Hubei Province no.2018CFA064,the National Science Fund for Distinguished Young Scholars no.51925104;the National Natural Science Foundation of China grant nos.51671081 and 51871162;Hong Kong ITC(ITS/287/17,GHX/002/14SZ);Health and Medical Research Fund(No.03142446).

摘　　要：A PLGA/Ti_(3)C_(2) hybrid coating was successfully deposited on the surface of magnesium-strontium(Mg-Sr)alloys.Compared with the corrosion current density(icorr)of the Mg-Sr alloy(7.13×10^−5 A/cm^2),the modified samples(Mg/PLGA/Ti_(3)C_(2))was lower by approximately four orders of magnitude(7.65×10^−9 A/cm^2).After near infrared 808 nm laser irradiation,the icorr of the modified samples increased to 3.48×10^−7 A/cm^2.The mechanism is that the local hyperthermia induced the free volume expansion of PLGA,and the increase in intermolecular gap enhanced the penetration of electrolytes.Meanwhile,the cytotoxicity study showed that the hybrid coating endowed the Mg-Sr alloy with enhanced biocompatibility.

关 键 词：MAGNESIUM Ti_(3)C_(2)Mxene Coating PHOTORESPONSIVE DEGRADATION 

分 类 号：TG13[一般工业技术—材料科学与工程]