Application of naturalβ-glucans as biocompatible functional nanomaterials  

作　　者：Xiaojie Li Peter Chi Keung Cheung 

机构地区：[1]Food and Nutritional Sciences,School of Life Sciences,The Chinese University of Hong Kong,Hong Kong,China

出　　处：《Food Science and Human Wellness》2019年第4期315-319,共5页食品科学与人类健康（英文）

摘　　要：Naturally-occurringβ-glucans are mostly investigated for their antitumor activity and immunomodulatory property.They have been widely regarded as a natural source for functional foods and pharmaceuticals.However,the physico-chemically stable and biocompatible properties ofβ-glucans are rarely explored as a coating material for nanomaterials to overcome the problems of aggregation and cytotoxicity.This article reviews on the exploration ofβ-glucans,in particular those derived from mushrooms,as a natural coating material to modify the surface properties of bioactive substances as a relatively simple and cost-effective strategy to produce stable and biocompatible nanohybrids used for biopharmaceutical use.It is envisaged that suchβ-glucan-based coating method will provide new opportunities to design biocompatible functional nanomaterials for wider clinical applications.

关 键 词：β-Glucans BIOCOMPATIBILITY BIOPHARMACEUTICALS NANOHYBRIDS 

分 类 号：R318.08[医药卫生—生物医学工程] TB383.1[医药卫生—基础医学]