双水平气道正压无创呼吸机辅助通气治疗重症哮喘患者的临床效果  

Clinical Effect of Bi-level Positive Airway Pressure Non-invasive Ventilation Assisted Ventilation on Severe Asthma

作　　者：范雪飞 FAN Xuefei(Department of Critical Care Medicine,Dandong Central Hospital,Dandong 118002,China)

机构地区：[1]丹东市中心医院重症医学科,辽宁丹东118002

出　　处：《中国医药指南》2020年第36期65-66,共2页Guide of China Medicine

摘　　要：目的探讨双水平气道正压无创呼吸机辅助通气治疗重症哮喘患者的临床效果。方法选取66例本院收治的重症哮喘患者作为研究对象,时间为2018年1月至2019年6月,根据随机数字表法将患者分为观察组(n=33,予以抗感染、祛痰剂、β受体激动剂、氨茶碱、糖皮质激素等对症支持治疗)和对照组(n=33,在对照组治疗基础上加以双水平气道正压无创呼吸机辅助通气治疗)。对比治疗前后两组患者的血气指标变化情况及临床疗效。结果治疗前,观察组及对照组的PaO2[(53.36±3.53)mmHg vs.(53.72±3.61)mmHg]、PaCO2[(69.97±3.51)mmHg vs.(69.72±3.73)mmHg]比较,差异无统计学意义(P>0.05)。治疗后,观察组患者的PaO2[(86.68±3.31)mmHg vs.(74.49±4.26)mmHg]明显高于对照组,PaCO2[(41.16±1.61)mmHg vs.(48.77±2.32)mmHg]明显低于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率为90.91%,对照组总有效率为63.64%,差异有统计学意义(P<0.05)。结论在重症哮喘患者中施以双水平气道正压无创呼吸机辅助通气治疗,可有效改善患者的血气指标,提高临床疗效。Objective To investigate the clinical effect of bi-level positive airway pressure noninvasive ventilator assisted ventilation in the treatment of severe asthma.Methods A total of 66 patients with severe asthma admitted to our hospital from January 2018 to June 2019 were selected as the research objects.According to the random number table method,the patients were divided into the observation group(33 cases)and the control group(33 cases).The patients in the control group were given anti infection,expectorant,beta agonist,aminophylline,glucocorticoid and other symptomatic support treatment,while the patients in the observation group were given bi-level treatment on the basis of the treatment in the control group.The changes of blood gas indexes and clinical efficacy of the two groups before and after treatment were compared.Results Before treatment,there was no significant difference in PaO2[(53.36±3.53)mm Hg vs.(53.72±3.61)mm Hg]and PaCO2[(69.97±3.51)mm Hg vs.(69.72±3.73)mm Hg]between the observation group and the control group(P>0.05).After treatment,PaO2[(86.68±3.31)mm Hg vs.(74.49±4.26)mm Hg]of the observation group was significantly higher than that of the control group,PaCO2[(41.16±1.61)mm Hg vs.(48.77±2.32)mm Hg]of the observation group was significantly lower than that of the control group,the difference was statistically significant(P<0.05).The total effective rate of the observation group was 90.91%,the control group was 63.64%,the difference was statistically significant(P<0.05).Conclusion The application of bi-level positive airway pressure noninvasive ventilator assisted ventilation in patients with severe asthma can effectively improve the blood gas index of patients and improve the clinical efficacy.

关 键 词：重症哮喘 辅助通气 双水平气道 正压通气 无创呼吸机 

分 类 号：R562.25[医药卫生—呼吸系统]