右美托咪定复合七氟醚硬膜外麻醉在小儿腹股沟疝修补术的应用  

Clinical appraisal of dexmedetomidine combined with sevoflurane epidural anesthesia in the repair of inguinal hernia in children

作　　者：黄彬斌 邹瑛 Huang Binbin;Zou Ying(Department of Anesthesiology,Maternal and Child Health Hospital of Shiyan City,Hubei Province,Shiyan 442000,China;Intensive Care Unit,Maternal and Child Health Hospital of Shiyan City,Hubei Province,Shiyan 442000,China)

机构地区：[1]湖北省十堰市妇幼保健院麻醉科,442000 [2]湖北省十堰市妇幼保健院重症监护室

出　　处：《中华疝和腹壁外科杂志（电子版）》2020年第6期693-696,共4页Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition)

摘　　要：目的探讨右美托咪定复合七氟醚硬膜外麻醉对小儿腹股沟疝修补术的应用效果。方法选取2016年1月至2019年1月,四川省资阳市人民医院行腹股沟疝修补术患儿90例,随机分为2组,其中对照组患儿采取七氟醚加常规药物硬膜外麻醉方式,试验组患儿在此基础上加入右美托咪定作为复合药液,比较2组患儿的血流动力学、镇静及苏醒期躁动评分及不良情况发生率。结果2组患儿在进入手术室时血压、心率比较,差异无统计学意义(P>0.05);而试验组患儿在插管时与手术结束后的血压、心率均显著低于对照组(P<0.05)。试验组患儿的镇静评分为(0.9±0.2)分,躁动评分为(0.5±0.4)分,均显著低于对照组(1.6±0.4)分、(1.5±0.5)分,差异均有统计学意义(P<0.05)。试验组患儿的麻醉并发症发生人数为4例,术后感染发生人数为2例,不良情况发生率明显低于对照组(P<0.05)。结论与对照组相比,七氟醚全麻下硬膜外复合右美托咪定注射可有效稳定小儿腹股沟疝修补术患儿的血流动力学情况,并且具有更为显著的镇静及镇痛效果,亦可降低患儿苏醒期躁动,对于患儿手术顺利进行及术后恢复具有积极意义,可在临床实践中进行广泛应用。Objective To explore the effect of dexmedetomidine combined with sevoflurane epidural anesthesia on the repair of inguinal hernia in children.Methods A retrospective analysis on the clinical data of 90 children undergoing pediatric inguinal hernia repair in the people's hospital of Ziyang City from January 2016 to January 2019 was carried out.And they were randomly divided into two groups.The control group was given sevoflurane anesthesia,and the experimental group was given dexmedetomidine combined with sevoflurane epidural anesthesia.The hemodynamics,sedation and agitation scores of the two groups were compared,as well as the incidence of adverse events.Results There were no significant differences in blood pressure and heart rate between the two groups of children on arrival in the operating room(P>0.05),while the hemodynamic data of the experimental group at the time of intubation and after the operation were significantly lower than those of the control group(P<0.05).The sedation score of the children in the experimental group was(0.9±0.2)and the restlessness score was(0.5±0.4),which were significantly lower than those of the control group(1.6±0.4,1.5±0.5,respectively;P<0.05);the number of anesthesia complications in the experimental group was 4 cases,and the number of postoperative infections was 2 cases.The incidence of adverse events in experimental group was significantly lower than that in the control group(P<0.05).Conclusion The epidural injection of dexmedetomidine combined with sevoflurane can effectively stabilize the hemodynamics of children undergoing inguinal hernia repair,and has more significant sedative and analgesic effects,and it can also reduce restlessness during the recovery period of children.It is significant for the smooth operation and postoperative recovery of children.It can be widely used in clinical practice.

关 键 词：右美托咪定 七氟醚 硬膜外麻醉 腹股沟疝 应用效果 

分 类 号：R726.1[医药卫生—儿科]