体质指数正常人群中的代谢综合征患病情况  

Prevalence of metabolic syndrome in people with normal body mass index

作　　者：王文捷 郭艳琴 严苗苗 刘安定[2] 吕永曼[1] 雷小妹 WANG Wen-jie;GUO Yan-qin;YAN Miao-miao;LIU An-ding;LV Yong-man;LEI Xiao-mei(Health Management Center,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430030,China;不详)

机构地区：[1]华中科技大学同济医学院附属同济医院体检中心,湖北武汉430030 [2]华中科技大学同济医学院附属同济医院实验医学研究中心

出　　处：《现代预防医学》2021年第2期198-200,218,共4页Modern Preventive Medicine

基　　金：国家自然科学基金项目(81300343)。

摘　　要：目的了解体质指数(BMI)正常人群多代谢异常与代谢综合征(MS)的患病情况。方法选取2016年1月—2017年12月健康体检人群为研究对象,以2004年中华医学会糖尿病学分会制订的MS诊断标准,符合纳入标准的正常BMI对象共5781名(男3069名,女2712名)。根据BMI的四分位数将调查对象分成Q1~Q4组计算性别、年龄别MS的患病率。结果5781名对象的MS患病率为12.71%(男性9.22%,女性16.67%,χ^2=71.92,P<0.001)。专业技术人员的MS患病率较其它职业人群显著增高(χ^2=19.76,P=0.001),低学历人群的MS患病率较高学历人群显著增高(χ^2=10.79,P=0.005)。男性随BMI升高(Q1~Q4)MS患病率由3.21%增至17.54%(χ^2=87.11,P<0.001);女性(Q1~Q4)MS患病率由7.32%增至29.78%(χ^2=147.66,P<0.001)。男性各个BMI组MS患病率均低于女性(Q1:3.21%vs 7.32%,χ^2=10.31,P<0.001;Q2:6.35%vs 10.26%,χ^2=8.64,P<0.001;Q3:9.72%vs 19.27%,χ^2=27.39,P<0.001;Q4:17.54%vs 29.79%,χ^2=28.11,P<0.001)。男性随年龄升高(≤40岁~≥60岁)MS患病率由3.43%增至13.15%(χ^2=67.09,P<0.001)、女性(≤40岁~≥60岁)MS患病率由10.72%增至24.25%(χ^2=54.43,P<0.001);随BMI升高(Q1~Q4),伴有MS组分异常的患病率由28.51%增至40.56%(χ^2=77.39,P<0.001)。结论BMI正常人群仍有一定多代谢异常和MS患病率,要注意BMI正常人群的代谢性健康风险管理。Objective To investigate the prevalence of multi-metabolic disorders and metabolic syndrome(MS) in people with normal body mass index(BMI). Methods A total of 5 781 subjects(3 069 males and 2 712 females) with normal BMI who underwent physical examinations in our Health Management Center during January 2016 and December 2017 and were diagnosed with MS according to the criteria proposed by Chinese Medical Association for Diabetes Mellitus in 2004 were selected. The subjects were divided into Q1 to Q4 groups according to the quartiles of BMI, and the prevalence of MS by gender and age was calculated. Results The total prevalence of MS was 12.71%(9.22% in men and 16.67% in women,χ2=71.92, P<0.001). The MS prevalence was significantly higher in professional technicians than in other occupational groups(χ2=19.76, P =0.001). People with low education level had higher MS prevalence than those with higher education level(χ2=10.79, P=0.005). Corresponding to the BMI increase from Q1 to Q4, the MS prevalence rose from 3.21% to 17.54%(χ2=87.11, P<0.001) in males and from 7.32% to 29.78%(χ2=147.66, P<0.001) in females. The prevalence of MS was lower in males than in females in all BMI groups(Q1: 3.21% vs 7.32%, χ2=10.31, P<0.001;Q2: 6.35% vs 10.26%, χ2=8.64, P<0.001;Q3: 9.72% vs 19.27%, χ2=27.39, P <0.001;Q4: 17.54% vs 29.79%, χ2=28.11, P <0.001). As age advanced, the prevalence of MS in males aged ≦40-≥60 years increased from 3.42% to 13.15%(χ2=67.09, P<0.001), and from 10.72% to24.25%(χ2=54.43, P<0.001) in females aged ≤40-≥60 years. The MS with abnormal MS components increased with BMI(Q1-Q4) from 28.51% to 40.56%(χ2=77.39, P<0.001). Conclusion People with normal BMI carry certain risk of metabolic abnormality and MS, and attention should be paid to their metabolic health risk management.

关 键 词：代谢综合征 体质指数 患病率 

分 类 号：R589[医药卫生—内分泌]