腹腔镜治疗胃十二指肠溃疡穿孔的应用及疾病转归情况  

Application of laparoscopy in the treatment of gastroduodenal ulcer perforation and its disease outcome

作　　者：陶欣 TAO Xin(Department of General Surgery,Liaoning Health Industry Group Fushun Mining Bureau General Hospital,Fushun 113006,China)

机构地区：[1]辽宁省辽宁健康产业集团抚顺市矿务局总医院普外科,113006

出　　处：《中国实用医药》2021年第1期36-39,共4页China Practical Medicine

摘　　要：目的分析腹腔镜治疗胃十二指肠溃疡穿孔的应用效果及患者疾病转归情况。方法80例胃十二指肠溃疡穿孔患者,采用计算机随机法分为观察组与对照组,各40例。对照组患者实施开腹手术治疗,观察组患者实施腹腔镜手术治疗。比较两组围手术期指标、生理应激指标、治愈率及并发症发生情况。结果观察组首次自主下床活动时间、胃肠功能恢复时间、住院时间均短于对照组,术中出血量少于对照组,差异有统计学意义(P<0.05)。观察组血清皮质醇(54.45±3.55)μg/L、甲肾上腺素(32.55±2.35)μg/L均低于对照组的(126.13±13.12)、(71.22±1.35)μg/L,差异有统计学意义(t=33.354、90.242,P<0.05)。观察组并发症发生率为5.00%(2/40),低于对照组的25.00%(10/40),差异有统计学意义(χ2=6.275,P<0.05)。两组治愈率均为100.00%(40/40),组间比较差异无统计学意义(P>0.05)。结论胃十二指肠溃疡穿孔患者采取腹腔镜手术治疗,可更好减轻手术应激反应,提高术后康复速度。Objective To analyze the practical effect and disease outcome of laparoscopy in the treatment of gastroduodenal ulcer perforation.Methods A total of 80 patients with gastroduodenal ulcer perforation were divided into observation group and control group according to computer random method,with 40 cases in each group.The control group was treated with open surgery,and the observation group was treated with laparoscopic surgery.The perioperative indicators,physiological stress indicators,cure rate and occurrence of complications were compared between the two groups.Results The first-time off-bed activity time,gastrointestinal function recovery time and hospitalization time of the observation group were shorter than those of the control group,and intraoperative blood loss was less than that of the control group,and the difference was statistically significant(P<0.05).The serum cortisol(54.45±3.55)μg/L and norepinephrine(32.55±2.35)μg/L of the observation group were lower than(126.13±13.12)and(71.22±1.35)μg/L of the control group,and the difference was statistically significant(t=33.354,90.242;P<0.05).The incidence of complications of the observation group was 5.00%(2/40),which was lower than 25.00%(10/40)of the control group,and the difference was statistically significant(χ2=6.275,P<0.05).The cure rate of the two groups were both 100.00%(40/40),and the difference was not statistically significant(P>0.05).Conclusion In the treatment of patients with gastroduodenal ulcer perforation,laparoscopic surgery can better reduce the surgical stress response and improve the speed of postoperative recovery.

关 键 词：腹腔镜 胃十二指肠溃疡穿孔 开腹手术 疾病转归情况 

分 类 号：R656.62[医药卫生—外科学]