单纯药物涂层球囊治疗冠状动脉分叉病变分支血管的效果评估  

Evaluation of the effect of simple drug-coated balloon in the treatment of branch vessels in coronary bifurcation lesions

作　　者：张斌 张玉睿 ZHANG Bin;ZHANG Yu-rui(Second Affiliated Hospital of Shandong First Medical University,Taian 271000,China)

机构地区：[1]山东第一医科大学第二附属医院,271000

出　　处：《中国实用医药》2021年第2期118-120,共3页China Practical Medicine

摘　　要：目的探究单纯药物涂层球囊治疗冠状动脉分叉病变分支血管的临床效果。方法60例冠状动脉分叉病变患者,通过随机数字表法分为对照组和实验组,每组30例。对照组在给予患者切除球囊血管形成术进行治疗,实验组给予患者单纯药物涂层球囊进行治疗。对比两组扩张后即刻、治疗后6个月的最小管腔直径(MLD)、直径狭窄及支架内再狭窄率。结果扩张后即刻,两组患者MLD、直径狭窄比较,差异无统计学意义(P>0.05);治疗后6个月,实验组MLD(1.89±0.21)mm长于对照组的(1.25±0.36)mm,实验组直径狭窄(31.74±17.65)mm短于对照组的(48.67±21.37)mm,实验组支架内再狭窄发生率6.67%低于对照组的30.00%,差异有统计学意义(P<0.05)。结论在冠状动脉分叉病变分支血管患者治疗过程中应用单纯药物涂层球囊具有良好临床效果,不仅能够改善其临床指标情况,而且有助于降低支架内再狭窄率,可以在临床实践中广泛应用及推广。Objective To discuss the clinical value of simple drug-coated balloon in the treatment of branch vessels in coronary bifurcation lesions.Methods A total of 60 patients with coronary bifurcation lesions were divided into control group and experimental group according to random numerical table,with 30 cases in each group.Patients in the control group were treated with resection balloon angiogenesis,and patients in the experimental group were treated with simple drug-coated balloon.The minimum lumen diameter(MLD),diameter stenosis and in-stent restenosis rate were compared between the two groups immediately after expansion and 6 months after treatment.Results Immediately after expansion,there was no statistically significant difference in MLD and diameter stenosis between the two groups(P>0.05).6 months after treatment,MLD(1.89±0.21)mm of the experimental group was higher than(1.25±0.36)mm of the control group,diameter stenosis(31.74±17.65)mm was shorter than(48.67±21.37)mm of the control group,and in-stent restenosis rate 6.67%was lower than 30.00%of the control group,and the difference was statistically significant(P<0.05).Conclusion Simple drugcoated balloon has good clinical effect in the treatment of patients with branch vessels in coronary bifurcation lesions,which can not only improve the clinical indicators,but also help reduce the rate of in-stent restenosis.It can be applied and promoted in clinical practice.

关 键 词：单纯药物涂层球囊 冠状动脉分叉病变分支血管 临床价值 

分 类 号：R541.4[医药卫生—心血管疾病]