多层螺旋CT和核素扫描对结节性甲状腺肿诊断的临床价值对比  

Comparison of clinical value of MSCT and radionuclide scanning in the diagnosis of nodular goiter

作　　者：黄东琼 许林[2] 邱冬梅[3] 李全[2] 冯真 HUANG Dongqiong;XU Lin;QIU Dongmei;LI Quan;FENG Zhen(Departmnet of Nuclear Medicine,Dazhou Central Hospital Dazhou Sichuan Province 635000;Medical Imaging Center,Dazhou Central Hospital Dazhou Sichuan Province 635000;Department of Common Breast,Dazhou Central Hospital Dazhou Sichuan Province 635000)

机构地区：[1]达州市中心医院核医学科,四川达州635000 [2]达州市中心医院医学影像中心,四川达州635000 [3]达州市中心医院普胸乳甲科,四川达州635000

出　　处：《实用放射学杂志》2021年第1期34-37,共4页Journal of Practical Radiology

摘　　要：目的对比多层螺旋CT(MSCT)和核素扫描对结节性甲状腺肿(NG)诊断的临床价值.方法回顾性分析经术后病理证实的100例甲状腺结节性病变患者临床资料,患者术前均行MSCT及核素扫描检查,以术后病理结果为金标准,比较MSCT、核素扫描单一诊断及二者联合诊断甲状腺病变的灵敏度、特异性、准确率,分析MSCT诊断NG与甲状腺癌(TC)的影像特点.结果100例患者经术后病理诊断NG41例,TC59例,共发现146个病变结节;核素扫描诊断NG21例,TC79例;CT诊断NG45例,TC55例;MSCT与术后病理诊断一致的NG(39例)、TC(53例)患者CT图像显示的病灶数目、病灶平均直径、增强边界、微小钙化、囊变、甲状腺边缘中断征及淋巴结异常情况比较,差异有统计学意义(P<0.05);MSCT与核素扫描联合诊断NG42例,TC58例;MSCT、核素扫描及二者联合诊断在NG与TC诊断中的灵敏度为91.52%、89.83%和94.92%,特异度为39.02%、95.12%和95.12%,准确率为70.00%、92.00%和95.00%.结论相较于核素扫描,MSCT在NG与TC的鉴别诊断中具有更高的诊断效能,NG与TC的MSCT图像在病灶数目、病灶平均直径、增强边界、微小钙化、囊变、甲状腺边缘中断征及淋巴结异常情况等方面表现有特异性,有助于定性诊断,二者联合诊断则可进一步提高诊断效能.Objective TO compare the clinical value of multi-slice-CT(MSCT)and radionuclide scanning in the diagnosis of nodular goiter(NG).Methods The clinical data of 100 patients with thyroid nodular lesions confirmed by postoperative pathology were analyzed retrospectively.MSCT and radionuclide scanning were performed on patients before operation.The postoperative pathological results were used as the gold standards,and the sensitivity,specificity and accuracy rate of MSCT,radionuclide scanning and the combination of the two methods were analyzed in the diagnosis of thyroid lesions,and the imaging features of MSCT on NG and thyroid carcinoma(TC)were analyzed.Results Among 100 patients,41 cases of NG and 59 cases of TC were diagnosed by postoperative pathology,and a total of 146 lesion nodules were found.21 cases of NG and 79 cases of TC were diagnosed by radionuclide scanning,and 45 cases of NG and 55 cases of TC were diagnosed by CT.There were statistically significant differences in the lesion quantity,mean lesion diameter,enhanced boundary,micro-calcification,cystic change,interrupted thyroid margin sign and lymph node abnormalities shown by CT images between NG patients(39 cases)and TC patients(53 cases)who were with consistent MSCT and postoperative pathological diagnosis(P〈0.05).And 42 cases of NG and 58 cases of TC were diagnosed by MSCT combined with radionuclide scanning.The sensitivity,specificity and accuracy rate of MSCT,radionuclide scanning and the combination of two methods in the diagnosis ofNG and TC were 91.52%,89.83%and 94.92%,39.02%,95.12%and 95.12%,and 70.00%,92.00% and 95.00%respcctivcly.Conclusion Compared with radionuclide scanning,MSCT has higher diagnostic efficacy in the differential diagnosis of NG and TC,and MSCT images of NG and TC have specificity in terms of lesion quantity,mean lesion diamctcr,cnhanccd boundary,micro-calcification cystic change,interrupted thyroid margin sign and lymph node abnormalities,which is helpful for qualitative diagnosis,and the combination of the two methods c

关 键 词：计算机体层成像 核素扫描 结节性甲状腺肿 

分 类 号：R814.42[医药卫生—影像医学与核医学] R581.3[医药卫生—放射医学]