双胎输血综合征临床特征及妊娠结局分析  

analysis of the clinical features and pregnancy outcomes in twin-transfusion syndrome

作　　者：唐艳妮 付春云[1] 陆月合 荆俊鹏 唐娟松 Tang Yanni;Fu Chunyun;Lu Yuehe;Jing Junpeng;Tang Juansong(Department of Ultrasound,Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region,Nanning,Guangxi 530003,China)

机构地区：[1]广西壮族自治区妇幼保健院超声科,广西南宁530003

出　　处：《影像研究与医学应用》2021年第1期31-32,36,共3页Journal of Imaging Research and Medical Applications

摘　　要：目的:分析双胎输血综合征(TTTS)的临床特征及妊娠结局。方法:收集2016-2018年在我院治疗的14例双胎输血综合征孕妇作为观察组,同期收入单绒毛膜双胎孕妇38例作为对照组,比较两组大脑中动脉收缩期峰值流速(MCA-PSV)、NT、孕周等参数差异,分析其妊娠结局。结果:胎儿出生孕周、MCA-PSV、NT厚度、脐静脉内径(UV-内径)、脐静脉峰值流速(UV-PSV)在两组间存在显著差异(P<0.05);孕妇年龄、DV-D波、DV-S波、DV-S/a、大脑中动脉阻力指数(MCA-RI)这些参数在两组间无统计学差异。14例TTTS中,6例(42.86%)引产;1例(7.14%)双胎中一胎行射频消融减胎术,另一胎继续妊娠至分娩;7例(50%)顺利分娩,均为急诊剖腹的早产儿。TTTS组中15例出生儿,经随访发现有3例异常。结论:本研究发现胎儿出生孕周、MCA-PSV、NT厚度、UV-内径、UV-PSV在TTTS组和对照组两组间存在显著差异,TTTS围产儿死亡率高,出生儿中有20%随访出现异常。Objective To investigate the clinical features and pregnancy outcomes in twin-twin transfusion syndrome(TTTS).Methods 14 TTTS and 38 monochorionic twins who were treated in our hospital from February 2016 to February 2018 were retrospectively analyzed.The differences of maternal age,NT,gestational weeks and other parameters between the two groups were compared,and the pregnancy outcomes were analyzed.Results There were significant differences between the two groups in gestational weeks,MCA-PSV,NT thickness,UV-diameter and UV-PSV.There was no statistical difference between the two groups in maternal age,DV-D wave,DV-S wave,DV-S/a and MCA-RI.Among the 14 TTTS,6 cases(42.86%)were induced labor;1 case(7.14%)was performed with radiofrequency ablation;the other 7 cases(50%)delivered their babies,but all were premature babies with emergency caesarean section.Among the 15 newborns with TTTS,3 cases were found abnormal after follow-up.Conclusion In this study,significant differences were found between TTTS group and control group in fetal gestation weeks,MCA-PSV,NT thickness,UV-diameter and UVPSV.TTTS had a high perinatal mortality,20%of babies with TTTS were found with abnormalities by follow-up visit.

关 键 词：双胎输血综合征 临床特征 妊娠结局 显著差异 

分 类 号：R445.1[医药卫生—影像医学与核医学]