绝经后膝骨关节炎的药物治疗进展  

A review on treating postmenopausal knee osteoarthritis with medicines

作　　者：陶帅[1] 姜宏[2] 戴瑜[1] 王铠[1] 俞鹏飞[2] 印红兵[1] 龚华惠 Tao Shuai

机构地区：[1]泰州市中医院,江苏泰州225300 [2]苏州市中医医院,江苏苏州215000

出　　处：《中医临床研究》2020年第34期141-145,共5页Clinical Journal Of Chinese Medicine

基　　金：泰州市科技支撑计划(社会发展)项目(TS201909)。

摘　　要：骨关节炎(Osteoarthritis,OA)是最常见的慢性关节疾病,50岁以后女性膝骨关节炎患病率明显高于绝经前女性和同期男性,目前病理机制不明确,药物治疗方法众多。文章分别从口服非甾体类抗炎药(Nonsteroidal Anti-inflammatory Drugs,NSAIDs)、对症慢作用药物(Symptomatic Slow-acting Drug for Osteoarthritis,SYSADOA)、雌激素类药物,关节腔内注射透明质酸、糖皮质激素、富血小板血浆(Platelet-rich Plasma,PRP)和中药外治、内服等方面进行论述,同时指出本病可从"天癸理论"入手,以补肾活血为治疗大法,以期为绝经后膝骨关节炎的治疗提供更有价值的指导。Osteoarthritis is the most common chronic joint disease. The prevalence of knee osteoarthritis in women after the age of 50 is significantly higher than that in men in the same period and premenopausal women. The pathological mechanism is unclear at present and there are many medicines treatments methods. From the perspective of NSAIDs,SYSADOA, estrogens medecines, intra-articular cavity injection of hyaluronic acid, glucocorticoid and PRP, and TCM medicine external treatment or internal treatment, treating the disease by invigorating the kidney and promoting blood circulation based on the Tian’gui theory(天癸理论) was given in the article, in order to provide more valuable guidance for the treatment of postmenopausal knee osteoarthritis.

关 键 词：绝经 膝骨关节炎 药物治疗 研究进展 

分 类 号：R322.72[医药卫生—人体解剖和组织胚胎学]