西藏地区红细胞单采治疗高原红细胞增多症的疗效研究  

Study on the efficacy of erythrocytapheresis for high altitude polycythemia in Tibet

作　　者：朱澍 罗布卓玛 方洁 次仁央宗 宗吉 普布旺堆 巴顿 乐飞 李啸扬[1,3] ZHU Shu;LUO Bu Zhuo Ma;FANG Jie;CI Ren Yang Zong;ZONG Ji;PU Bu Wang Dui;BA Dun;YUE Fei;LI Xiaoyang(Department of Hematology,Shigatse People′s Hospital,Shigatse,Tibet 875000,China;Finance Section,Obstetrics and Gynecology Hospital,Fudan University,Shanghai 200011,China;Department of Hematology,Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China)

机构地区：[1]西藏自治区日喀则市人民医院血液科,875000 [2]复旦大学附属妇产科医院财务科,上海200011 [3]上海交通大学医学院附属瑞金医院血液科,上海200025

出　　处：《重庆医学》2021年第3期402-405,共4页Chongqing medicine

基　　金：2019年度西藏自治区自然基金项目[XZ2019ZR-ZY50(Z)]。

摘　　要：目的探讨红细胞单采治疗对高原红细胞增多症的疗效。方法选取2017年10月至2018年12月80例高原红细胞增多症且血红蛋白超过250 g/L的患者为研究对象,分为红细胞单采组(n=52)和传统治疗组(n=28),比较两组临床疗效及经济负担。结果与传统治疗组比较,红细胞单采组治疗后血常规指标恢复情况更好,治疗后1年疾病进展率更低(75.0%vs.11.5%),并发症发生率更低(0 vs.17.9%),治疗总费用更低[(13584.08±292.85)元vs.(17655.34±973.23)元],差异有统计学意义(P<0.05)。结论红细胞单采治疗是高原红细胞增多症的高效治疗方案。Objective To explore the curative effect of erythrocytapheresis on high altitude polycythemia.Methods From October 2017 to December 2018,80 patients with high altitude polycythemia and hemoglobin exceeding 250 g/L were selected as the objects,and they were divided into the erythrocytapheresis group(n=52)and the traditional treatment group(n=28),compared the clinical efficacy and economic burden of the two groups.Results Compared with the traditional treatment group,the erythrocytapheresis group has better recovery of blood routine indicators after treatment,lower disease progression rate after 1 year treatment(75.0%vs.11.5%),lower complication rate(0 vs.17.9%),lower total treatment cost[(13584.08±292.85)CNY vs.(17655.34±973.23)CNY],the difference was statistically significant(P<0.05).Conclusion Erythrocytapheresis is an effective treatment plan for high altitude polycythemia.

关 键 词：红细胞增多症 红细胞单采术 治疗结果 并发症 治疗费用 

分 类 号：R457.3[医药卫生—治疗学]