2009-2018年内蒙古自治区手足口病流行病学及季节性特征  

Epidemiological characteristics of hand-foot-mouth disease in Inner Mongolia Autonomous Region from 2009 to 2018

作　　者：张樱樱 王艳玲 刘颖 云瀚漩 赵乐 赵静 ZHANG Ying-ying;WANG Yan-ling;LIU Ying;YUN Han-xuan;ZHAO Le;ZHAO Jing(Department of Child Hygiene and Health Education,School of Public Health,Inner Mongolia Medical University,Hohhot 010000,China)

机构地区：[1]内蒙古医科大学公共卫生学院儿童卫生与健康教育学教研室,呼和浩特010000

出　　处：《中华疾病控制杂志》2021年第1期60-65,共6页Chinese Journal of Disease Control & Prevention

基　　金：内蒙古卫生计生科研计划项目(201702048)。

摘　　要：目的探讨内蒙古自治区2009-2018年手足口病流行病学和季节性特征。方法对内蒙古自治区2009-2018年手足口病(hand-foot-mouth disease, HFMD)监测数据进行统计分析,采用集中度和圆形分布法分析其季节性特征。结果 2009-2018年内蒙古自治区共178 063例报告病例,年均报告发病率是71.99/10万,发病率总体呈下降趋势(χ^2趋势=3 584.162,P<0.001)。累计报告重症病例数为1 216例,总体呈下降趋势(χ^2趋势=8.772,P<0.001)。发病集中度M=0.876,有很强的季节性;圆形分布r=0.523,α=209.446°(144.187°, 274.705°)(Z=48 660.177,P<0.001),发病高峰日为7月16日,流行高峰期为5月2日至9月26日。重症集中度M=0.919,有严格的季节性;圆形分布r=0.592,α=210.688°(152.025°, 269.352°)(Z=426.240,P<0.001),重症高峰日为8月3日,重症高峰期为6月4日至11月1日;乌海市发病率最高(176.91/10万),不同盟市年均发病率差异有统计学意义(χ^2=1 548.865,P<0.001),Moran’s Index=-0.023(P=0.688),提示不存在地区聚集性;发病人群以≤10岁儿童(98.82%)为主,以散居儿童(48.50%)和幼托儿童(42.31%)为主,男女发病率差异有统计学意义(χ^2=30.482,P<0.001)。结论内蒙古自治区HFMD发病率总体呈逐年下降趋势,但仍需继续做好防控工作。Objective To analyzed the epidemiological and seasonal characteristics of hand-foot-mouth disease(HFMD) in Inner Mongolia Autonomous Region from 2009 to 2018. Methods The surveillance data of HFMD in Inner Mongolia Autonomous Region from 2009 to 2018 were analyzed using statistic methods, and concentration method and circular distribution method were used to analyze the seasonal variations. Results A total of 178 063 cases were reported in Inner Mongolia Autonomous Region from 2009 to 2018, with an annual average reported incidence of 71.99 per 100 000. The overall incidence showed a downward trend(χ^2trend=3 584.162, P<0.001). A total of 1 216 severe cases were reported, revealing an overall downtrend(χ^2trend=8.772, P<0.001). The incidence concentration ratio M-value was 0.876, exhibiting a strong seasonal characteristic. The concentration trend of HFMD circular distribution was 0.523, α=209.446°(144.187°, 274.705°)(Z=48 660.177, P<0.001). The incidence was mainly reported between May 2 and September 26 and peaked on July 16. The severe cases concentration ratio M-value was 0.919, indicating a strict seasonality. The concentration trend of severe cases circular distribution was 0.592, α=210.688°(152.025°, 269.352°)(Z=426.240, P<0.001). The most common peak day of severe cases was August 3, and the peak season was from June 4 to November 1. The incidence in Inner Mongolia Autonomous Region Wuhai City was highest(176.91/100 000), and the difference of the average annual incidence in different cities was statistically significant(χ^2=1 548.865, P<0.001). Moran’s Index was-0.023(P=0.688), suggesting that there was no regional aggregation. The cases were mainly concentrated in the population under 10 years old which accounted for 98.82%, in which scattered children and Kindergarten children accounted for 48.50% and 42.31%, respectively. There was statistically difference in morbidity between men and women(χ^2=30.482, P<0.001). Conclusions Though the incidence of HFMD in Inner Mongolia Autonomous Region

关 键 词：手足口病 流行病学 季节性分布 集中度 圆形分布法 

分 类 号：R510.4[医药卫生—内科学]