超声引导下射频消融术治疗乳腺良性结节疗效观察及影响因素分析  

Ultrasound Guided Radiofrequency Ablation for Benign Breast Nodules and its Influencing Factors

作　　者：邵嘉涛[1] 于韦韦[1] 刘悦[1] SHAO Jia-tao;YU Wei-wei;LIU Yue(The Third People's Hospital of Dalian,Dalian 116033)

机构地区：[1]大连市第三人民医院,辽宁大连116033

出　　处：《医学临床研究》2021年第1期72-75,共4页Journal of Clinical Research

摘　　要：【目的】探讨超声引导下射频消融术治疗乳腺良性结节疗效及影响因素。【方法】选取2018年1月至2019年2月本院收治的62例乳腺良性结节患者的临床资料,共98个结节。患者均进行超声引导下射频消融术,在常规超声模式下,测量记录治疗前后不同时间消融灶的体积,并计算所有消融灶体积减小情况,在超声E成像模式下检测记录所有消融灶弹性Ratio值,采用Pearson相关性分析结节大小、乳腺生理分期、结节象限与消融体积减小率的相关性。【结果】术后1、3、6、9、12个月,患者消融灶体积较术前逐渐缩小,差异有统计学意义(P<0.05);患者消融灶体积减小率逐渐增高,差异有统计学意义(P<0.05);患者弹性Ratio比值较治疗前呈上升趋势,差异有统计学意义(P<0.05)。术前和术后消融灶弹性Ratio比值与消融灶体积呈现负相关性(r=-3.87,P=0.026<0.05);与术后消融灶体积减小率呈现正相关性(r=0.24,P=0.030<0.05)。术后消融灶体积减小率与生理分期、象限位置无明显相关性(r生理分期=0.549,P=0.884;r象限位置=0.354,P=0.721);术后消融灶体积减小率与结节大小呈显著正相关性,差异有统计学意义(r=3.971,P=0.040<0.05)。直径<1 cm结节与1〜3 cm结节术后消融灶体积减小率呈上升趋势,差异有统计学意义(P<0.05);直径1〜3 cm结节术后消融灶体积减小率明显高于<1 cm直径结节,差异具有统计学意义(P<0.01)。【结论】超声引导下射频消融术治疗乳腺良性结节临床疗效显著,结节大小可能是影响患者术后消融灶吸收效果的因素,1〜3 cm直径结节者术后消融灶吸收较快。【Objectivc】To investigate the effect of the ultrasound guided radiofrequency ablation on benign breast nodules treatment and its influencing factors.【Methods】A total of 62 patients with benign breast nodules(98 nodules in total)treated in our hospital from January 2016 to May 2017 were selected for the study.All patients underwent ultrasound-guided radiofrequency ablation and their clinical data were collected.Then the preoperalive and postoperative values were calculated,including monthly record of focal ablation volume,lesion reduction of all focal ablation volume,and elasticity ratio of ablation lesions in the ultrasound E imaging mode.Then the correlations among the nodule size,breast physiology stages,nodal position quadrant and focal ablation volume reduction decrease were analyzed through the Pearson corrdation analysis.【Results】The postoperative focal ablation volume was decreased at 1,3,6,9 and 9 months after operation(P<0.05);The postoperative focal ablation volume reduction rate was in creased accordingly,and the difference was statistically significant(P<0.05).The postoperative elasticity Ratio showed an increasing trend(P<0.05).The preoperative and postoperative elasticity Ratio was negatively correlated with preoperative and postoperative focal ablation volume(r=-3.87,P=0.026),while it was positively correlated with the postoperative focal ablation volume rcduclion rate(r=0.014,P=0.030).The postoperative focal ablation volume reduction rate was not correlated with die breast physiology stages and nodal position quadrant(P>0.05),but it was positively corrdalcd with the nodule size(t=3.971,P=0.040).Nodules with a diameter of less than 1 cm and nodules with a diameter of 1 to 3 cm showed an upward irend in the reduction rate of ablation foci after optfration,and the difference was statistically significant(P<0.05).Nodules with a diameter of 1 to 3 cm after the operation decreased in volume.The rale was significantly higher than that of<1 cm diameter nodules;and the difference was statistica

关 键 词：结节病/影像诊断 乳腺疾病/影像诊断 乳腺疾病/治疗 导管消融术 治疗结果 影响因素分析 

分 类 号：R655.82[医药卫生—外科学]