运动调控高尿酸血症研究述评  

Review on Hyperuricemia Regulated by Exercise

作　　者：唐璐 杨麟[2] 陈建新[2] 陈亮 蒋成丹 李猛 谭婧 千少文[4] 陈晓艳 刘刚[2] TANG Lu;YANG Lin;CHEN Jian-xin;CHEN Liang;JIANG Cheng-dan;LI Meng;TAN Jing;QIAN Shao-wen;CHEN Xiao-yan;LIU Gang(School of Physical Education and Sports Sciences,South China Normal University,Guangzhou,Guangdong 510006,China;School of Sports and Health,Guangzhou University of Chinese Medicine,Guangzhou,Guangdong 510006,China;Department of Pharmacy,Affiliated TCM Hospital of Guangzhou Medical University,Guangzhou,Guangdong 510006,China;PE College,Wuhan Sports University,Wuhan,Hubei 430079,China;School of Economics and Trade,Guangdong Institute of Polytechnic and Commerce,Guangzhou,Guangdong 510510,China)

机构地区：[1]华南师范大学体育科学学院,广东广州510006 [2]广州中医药大学体育与健康学院,广东广州510006 [3]广州医科大学附属中医医院药学部,广东广州510006 [4]武汉体育学院体育教育学院,湖北武汉430079 [5]广东工贸职业技术学院经济贸易学院,广东广州510510

出　　处：《体育研究与教育》2021年第1期84-90,共7页Sports Research and Education

摘　　要：高尿酸血症(hyperuricemia,HUA)是由于尿酸排泄减少、嘌呤代谢紊乱和尿酸持续升高而引起单钠尿酸盐结晶体析出并沉积于组织或器官而形成的代谢性疾病。HUA的发病原因较为复杂,与年龄、性别、肥胖、饮食、遗传和运动不足等因素有关。近年来,以非药物治疗手段为主的运动疗法,正逐步被医学临床应用并取得了较好的预防和治疗效果,但机制尚未完全明确。建议未来以不同运动模式介导HUA相关分子靶点的系列研究,进一步丰富和充实运动刺激信号调控HUA的分子信号理论。Hyperuricemia(HUA)is a metabolic disease caused by the precipitation of monosodium urate crystals and their deposition in tissues or organs due to the decreased excretion of uric acid,the disorder of purine metabolism and the continuous rise of uric acid.The pathogenesis of HUA is complex,which is related to age,gender,obesity,diet,heredity and insufficient exercise.In recent years,non-drug therapy has been gradually applied in human clinical practice and has achieved good results in prevention and treatment.But the mechanism is not yet fully clear.In the future,it is suggested to conduct a series of studies on related molecular targets of HUA mediated by different movement patterns,so as to further enrich the molecular signal transduction theory of HUA regulated by exercise stimulation signals.

关 键 词：运动 高尿酸血症 人体试验 动物实验 

分 类 号：G804.2[文化科学—运动人体科学]