烟叶中茄尼醇提取纯化及应用研究进展  

Research progress on extraction,purification and application of solanesol from tobacco leaves

作　　者：姚雯 彭健[1] 顾丽莉[1] 杜康 张花 张尉 YAO Wen;PENG Jian;GU Lili;DU Kang;ZHANG Hua;ZHANG Wei(Faculty of Chemical Engineering,Kunming University of Science and Technology,Kunming 650500,China)

机构地区：[1]昆明理工大学化学工程学院,昆明市650500

出　　处：《烟草科技》2021年第1期104-112,共9页Tobacco Science & Technology

基　　金：云南省烟草公司2018年度科技计划项目“打叶复烤烟草芳香物回收应用研究”(2018530000242025)。

摘　　要：当前企业生产的茄尼醇存在着纯度低、色素含量高等问题,在很大程度上影响了茄尼醇的提取效果,导致规模化生产高纯度茄尼醇产品存在一定难度。针对这一现象,从茄尼醇的化学、物理性质等方面对茄尼醇进行剖析,重点探讨了超临界萃取、超声波提取、微波萃取以及溶剂浸取等方法提取茄尼醇的优缺点;综述了茄尼醇粗品纯化得到高纯度茄尼醇的方法及茄尼醇在生物活性以及生物医药中的应用进展。结果表明:茄尼醇粗品采用超声辅助溶剂萃取法所用的设备和工艺均比较简单;茄尼醇精品提取采用层析方法较多,但工艺复杂,且耗时长;分子印迹法将成为一种极具潜力的纯化茄尼醇的手段;茄尼醇在生物活性和医药开发领域具有极好的前景。Currently produced solanesol is often low purity with high pigment contents, negatively influencing the extraction of high-purity solanesol in scale production. This review analyzed solanesol's chemical and physical properties and compared its extraction by supercritical extraction, ultrasonic extraction, microwave extraction and solvent extraction. Methods used to purify crude solanesol to obtain high-purity solanesol and the applications of solanesol in biology and biomedicine were reviewed. The results showed that the equipment and technology of ultrasonic assisted solvent extraction for crude solanesol products were relatively simple. High purity solanesol extractions were mostly based on complex and time-consuming chromatographic technologies.The molecular imprinting method was a potential method for purifying solanesol in the future. Solanesol had great potentials in the fields of biological and pharmaceutical development.

关 键 词：茄尼醇 烟叶 提取 纯化 应用 

分 类 号：TS49[农业科学—烟草工业]