Cytogenetic biodosimetry for radiation accidents in China  

作　　者：Lin Han Yu Gao Ping Wang Yumin Lyu 

机构地区：[1]Department of Toxicology,Henan Institute for Occupational Medicine,Zhengzhou,450052,China [2]National Institute for Radiological Protection,Chinese Center for Disease Control and Prevention,Beijing,100088,China

出　　处：《Radiation Medicine and Protection》2020年第3期133-139,共7页放射医学与防护（英文）

基　　金：This work was supported by Key Science and Technology Project of Henan Province,China,IDs:142102310086;Medical Science and Technology Reseach of Henan Province,China,IDs:LHGJ20190815。

摘　　要：Cytogenetic indicators,especially dicentric chromosomes,have been globally considered the gold standard of biological dose estimation for more than 60 years.The application of these indicators to biological dose estimation in victims of radiation accidents in China has undergone approximately 40 years of development and thus provides more accurate information for the clinical diagnosis and patients’treatment.This paper reviews the application and future development of cytogenetic indicators,including chromosomal aberrations(dicentric chromosomes and chromosomal translocations),cytokinesis-block micronuclei,nucleoplasmic bridges,and premature condensation chromosome ring,as biodosimeters in China.

关 键 词：BIODOSIMETRY CYTOGENETICS Chromosomal aberrations Cytokinesis-block micronuclei Nucleoplasmic bridges Premature condensation chromosome ring 

分 类 号：R81[医药卫生—放射医学]