Can bone mineral density affect intra-operative blood loss of mini-invasive posterior lumbar interbody fusion?  

作　　者：Yong He Chao Liu Yue Huang 

机构地区：[1]Department of Orthopaedics,Sir Run Run Shaw Hospital,Zhejiang University School of Medicine,Hangzhou 310016,China [2]Key Laboratory of Musculoskeletal System Degeneration and Regeneration Translational Research of Zhejiang Province,Hangzhou 310016,China

出　　处：《Laparoscopic, Endoscopic and Robotic Surgery》2020年第3期66-69,共4页腔镜、内镜与机器人外科（英文）

基　　金：The study was funded by Zhejiang Provincial Nature Science Foundation of China(LY17H060006);Zhejiang Provincial Medical and Health Science Project(2017198461).

摘　　要：Objective:Many factors affect intraoperative blood loss(BL)in mini-invasive posterior lumbar interbody fusion(PLIF)procedures,but only few has examined.Specifically,the impact of bone mineral density(BMD)levels on intraoperative BL.This study aims to examine the correlation between these two factors.Methods:Retrospective review of 120 patients with low back disorders who were scheduled to undergo mini-invasive PLIF from October 2018 to October 2019 was performed.Patients were divided into two groups based on BMD of the lumbar spine:normal group and abnormal group(osteoporosis and osteopenia).Comparison of age,gender,BMD,BL,BMI,prothrombin time,activated partial thromboplastin time,haemoglobin concentration,intraoperative mean arterial pressure,platelet count,and operative time(OT)between the two groups,and correlation analysis of BMD and BL were conducted.Results:The mean BL of patients in the abnormal group was remarkably higher than that in the normal group:357.22±152.55 ml and 259.37±125.90 ml respectively(p<0.001).The partial correlation coefficient between BL and BMD was0.45(p<0.001).The results of univariate regression analysis demonstrated that only BMD,gender,and OT were related to BL(BMD,r=0.427,p<0.001;gender,r=0.211,p=0.024;OT,r=0.318,p=0.001).While multivariate linear regression analysis demonstrated that patients with lower BMD and longer OT had a higher amount of intraoperative BL(p<0.001).Conclusions:BMD is an important factor influencing intraoperative BL in mini-invasive PLIF.It should be assessed routinely as a part of the preoperative examination to improve preoperative assessment and ensure patient safety.

关 键 词：Bone mineral density Blood loss Mini-invasive posterior lumbar interbody FUSION 

分 类 号：R58[医药卫生—内分泌]