基于中医“治未病”理论的健康管理法干预高同型半胱氨酸血症疗效观察  

Clinical Observation of Health Management Intervention on Hyperhomocysteinemia Based on “Preventive Treatment of Disease” Theory of Traditional Chinese Medicine

作　　者：吴梦玮[1] 刘金民[2] WU Mengwei;LIU Jinmin(Beijing University of Chinese Medicine,Beijing 100029,China;Dongfang Hospital,Beijing University of Chinese Medicine,Beijing 100078,China)

机构地区：[1]北京中医药大学,北京100029 [2]北京中医药大学东方医院,北京100078

出　　处：《辽宁中医杂志》2020年第12期114-117,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金面上项目(81702623);北京中医药大学东方医院1166人才培养计划中青年专家(040204001001002027);北京中医药大学基本科研青年教师项目(2017-JMS-038)。

摘　　要：目的探讨基于中医"治未病"理论的健康管理法干预高同型半胱氨酸血症的临床疗效。方法自2018年1月—2019年9月,筛选出70例该院收治的高同型半胱氨酸血症患者,随机分为两组,即对照组和干预组,各35例,对照组给予常规西医治疗,干预组在对照组的基础上加用基于中医"治未病"理论的健康管理法进行治疗,疗程均为3个月。观察两组患者中医症状积分、治疗前后患者血同型半胱氨酸指标改善情况,并比较两组临床疗效。结果对比治疗前后两组中医症状积分变化情况,相较对照组,治疗组患者症状积分降低幅度更大,结果差异有统计学意义(P <0.05);治疗后,两组血同型半胱氨酸指标均有改善(P <0.05),且较对照组,干预组改善更显著(P <0.05);治疗后,干预组临床总有效率为94.29%(33/35),对照组临床总有效率为82.86%(29/35),干预组治疗效果更理想(P <0.05)。结论基于中医"治未病"理论的健康管理法可显著消除高同型半胱氨酸血症患者临床症状和体征,降低血同型半胱氨酸指标,提高临床疗效,对多种疾病的预防均有意义,值得临床应用。Objective The purpose of this study was to investigate the influence of health management intervention based on"preventive treatment of disease"theory of traditional Chinese medicine on clinical efficacy of hyperhomocysteinemia.Methods Seventy hyperhomocysteinemia patients admitted to our hospital from January 2018 to September 2019 were selected and randomly divided into treatment group and control group with 35 cases in each group according to the table of random number.The control group was administered with conventional western treatment,while the treatment group was administered with health management intervention based on"preventive treatment of disease"theory of traditional Chinese medicine on the basis of the control group.The patients in both groups were treated for 3 months.We observed the changes of TCM symptom scores,improvement of blood homocysteine indexes before and after treatment in the two groups,and compared the clinical efficacy between the two groups.Results Comparing the changes of TCM symptom scores before and after treatment between the two groups,the reduction of symptom scores in the treatment group was more significant than that in the control group with significant difference( P < 0.05).The blood homocysteine indexes of the two groups were significantly improved before and after treatment( P < 0.05),and the improvement in the intervention group was more significant than that in the control group( P < 0.05).After treatment,the total clinical effective rate of the treatment group and control group was 94.29%( 33/35) and 82.86%( 29/35),respectively.The clinical effect of the treatment group was better than that of the control group( P < 0.05).Conclusion The health management intervention based on"preventive treatment of disease"theory of traditional Chinese medicine can improve the clinical symptoms and signs of patients with hyperhomocysteinemia and reduce the level of blood homocysteine.It has good therapeutic effect on hyperhomocysteinemia and can effectively prevent the occurrence of

关 键 词：“治未病”理论 健康管理法 高同型半胱氨酸血症 临床疗效 

分 类 号：R552[医药卫生—血液循环系统疾病]