血液灌流联合血液透析技术在终末期肾病的治疗效果观察  

Observation on the therapeutic effect of hemoperfusion combined with hemodialysis in end-stage renal disease

作　　者：梁丽[1] LIANG Li(Department of Nephrology Hematology,The First People's Hospital of Aksu,Xinjiang,Aksu,843000,China)

机构地区：[1]新疆阿克苏地区第一人民医院肾病血液科,新疆阿克苏843000

出　　处：《新疆医学》2020年第11期1162-1164,共3页Xinjiang Medical Journal

摘　　要：目的观察血液灌流技术联合血液透析技术对终末期肾病的临床治疗效果。方法选择自2017年1月到2019年10月期间,阿克苏地区第一人民医院收治的终末期肾病患者60例,并按随机数字表法分为观察组、常规组,各30例。常规组采用血液透析治疗,观察组予以血液透析技术联合血液灌流。比较两组治疗前、治疗6个月后两组肾功能、血常规及生化指标水平。结果两组治疗前Scr、BUN水平比较,差异无统计学意义(P>0.05);治疗后两组均较本组治疗前改善,且观察组低于常规组,但差异无统计学意义(P>0.05)。两组治疗前血常规及生化指标水平比较,差异无统计学意义(P>0.05);治疗后两组均较本组治疗前改善,且观察组iPTH、hs-CRP低于常规组,SF、HCT、Hb水平高于常规组,差异有统计学意义(P<0.05)。结论针对终末期肾病患者,给予血液透析联合血液灌流技术进行治疗,对于提高患者肾功能、改善微炎症状态与营养状况有着重要意义,值得推广。Objective To observe the clinical effect of hemoperfusion technique combined with hemodialysis technique on end-stage renal disease.Methods From January 2017 to October 2019,60 patients with end-stage renal disease admitted to the first people’s hospital of Aksu Prefecture were selected and divided into observation group and routine group,30 cases in each group.The routine group was treated with hemodialysis,and the observation group was treated with hemodialysis combined with hemoperfusion.The renal function,blood routine and biochemical index levels between the two groups were compared before and 6 months after treatment.Results There was no statistically significant difference in the levels of Scr and BUN between the two groups before treatment(P>0.05).But levels of Scr and BUN after treatment between the two groups were better than those before treatment.And the data in the observation group was lower than that in the conventional group,but the difference was not statistically significant(P>0.05).The comparison of blood routine and biochemical index levels between the two groups before treatment was not statistically significant(P>0.05).After treatment,blood routine and biochemical index levels in both groups were improved compared with those before treatment,and the i PTH and hs-CRP in the observation group were lower than those in the conventional group.SF,the levels of HCT and Hb were higher than those of the conventional group,and the difference was statistically significant(P<0.05).Conclusions For patients with end-stage renal disease,the treatment of hemodialysis combined with hemoperfusion is of great significance for improving the renal function of patients,improving the micro-inflammatory state and nutritional status,and it is worthy of promotion.

关 键 词：血液透析 血液灌流 终末期肾病 肾功能 

分 类 号：R559[医药卫生—血液循环系统疾病]