尿常规与尿微量蛋白检测在糖尿病早期肾损伤中的诊断价值研究  

Study on the diagnostic value of urine routine and microalbuminuria test for early renal injury in diabetes mellitus

作　　者：徐娜 XU Na(Zhuanghe Central Hospital,Dalian 116400,China)

机构地区：[1]庄河市中心医院,116400

出　　处：《中国现代药物应用》2021年第3期21-23,共3页Chinese Journal of Modern Drug Application

摘　　要：目的分析糖尿病早期肾损伤应用尿常规与尿微量蛋白(mALB)检测的诊断价值。方法选取63例糖尿病早期肾损伤患者作为肾损伤组,60例糖尿病非肾损伤患者作为糖尿病组;另选取62例健康体检者作为对照组。对三组研究对象进行尿常规与mALB检测,比较三组尿常规和mALB检测阳性率及mALB和糖化血红蛋白(HbA1c)水平。结果肾损伤组尿常规检测阳性率92.48%和mALB检测阳性率100.00%均高于糖尿病组的43.33%、63.33%和对照组的0、8.06%,差异有统计学意义(P<0.05);糖尿病组尿常规和mALB检测阳性率均高于对照组,差异有统计学意义(P<0.05)。三组mALB检测阳性率均高于尿常规检测阳性率(P<0.05)。肾损伤组mALB水平(210.56±43.26)mg/L和HbA1c水平(11.26±2.08)%均高于糖尿病组的(98.56±22.07)mg/L、(9.37±3.26)%和对照组的(15.26±3.24)mg/L、(4.56±0.27)%,差异有统计学意义(P<0.05);糖尿病组的mALB和HbA1c水平均高于对照组,差异有统计学意义(P<0.05)。结论对糖尿病患者使用尿常规与mALB检测诊断可以判断是否存在早期肾损伤,诊断效果显著。Objective To analyze the diagnostic value of urine routine and microalbuminuria(mALB)test for early renal injury in diabetes mellitus.Methods There were 63 diabetes mellitus patients with early renal injury selected as renal injury group,60 diabetes mellitus patients without early renal injury as diabetes group,and another 62 healthy subjects as the control group.The urine routine and mALB of the three groups were tested,and the positive rates of urine routine and mALB test and the levels of mALB and glycosylated hemoglobin(HbA1c)of the three groups were compared.Results The positive rate of urine routine and mALB test in renal injury group were 92.48%and 100.00%,which were higher than those in diabetes group[43.33%and 63.33%]and control group[0 and 8.06%],and the difference was statistically significant(P<0.05);the levels of mALB and HbA1c of renal injury group were(210.56±43.26)mg/L and(11.26±2.08)%,which were all higher than diabetes group[(98.56±22.07)mg/L and(9.37±3.26)%]and control group[(15.26±3.24)mg/L and(4.56±0.27)%],and the difference was statistically significant(P<0.05);the levels of mALB and HbA1c of diabetes group were higher than those of the control group,and the difference was statistically significant(P<0.05).Conclusion Urine routine and mALB test for patients with diabetes mellitus can determine whether there is early kidney damage,and the diagnostic effect is significant.

关 键 词：糖尿病 早期肾损伤 尿常规 尿微量蛋白 

分 类 号：R587.2[医药卫生—内分泌] R692.9[医药卫生—内科学]