以单侧胸腔积液为首发表现的原发性干燥综合征1例报道并文献复习  

A case report and literature review of primary Sjogren's syndrome with unilateral pleural effusion as the initial manifestation

作　　者：朱东全 李清贤[1] ZHU Dongquan;LI Qingxian(Respiratory and Critical Care Medicine Department,the Third People's Hospital of Zhengzhou,Zhengzhou 450000,China)

机构地区：[1]郑州市第三人民医院呼吸与危重症医学科,河南郑州450000

出　　处：《临床医学研究与实践》2021年第4期19-22,共4页Clinical Research and Practice

摘　　要：干燥综合征是一种主要累及外分泌腺体的慢性炎症性自身免疫疾病。以单侧胸腔积液为首发表现而无口干、眼干等典型表现的干燥综合征极其罕见,极易误诊误治。本文主要介绍1例以右侧胸腔积液反复发作1年余的病例,先后经抗感染、抗结核治疗均无效,最后明确为干燥综合征继发的胸腔积液;旨在探讨以单侧胸腔积液为首发表现的原发性干燥综合征的临床特点和治疗措施,以提高广大临床医师对以单侧胸腔积液为首发表现的干燥综合征的认识。Sjogren's syndrome is a chronic inflammatory autoimmune disease which mainly involves exocrine glands.Sjogren's syndrome with unilateral pleural effusion as the initial manifestation and without typical manifestations such as dry mouth and dry eyes is extremely rare,which is easy to be misdiagnosed and mistreated.This paper mainly introduces a case of right pleural effusion with repeated attack for more than 1 year,which has been failed by anti-infection and anti-tuberculosis treatment successively,and finally it is clearly identified as a pleural effusion secondary to Sjogren's syndrome;to investigate the clinical characteristics and treatment measures of primary Sjogren's syndrome with unilateral pleural effusion as the initial manifestation,so as to improve the understanding of the majority of clinicians on Sjogren's syndrome with unilateral pleural effusion as the initial manifestation.

关 键 词：干燥综合征 胸腔积液 SSA抗体 可溶性核蛋白抗体 

分 类 号：R593.2[医药卫生—内科学] R442.8[医药卫生—诊断学]