脊柱内固定术后感染的危险因素及对策分析  

Analysis of risk factors and countermeasures of infection after spinal internal fixation

作　　者：赵海峰 石道勇 ZHAO Haifeng;SHI Daoyong(Pingli County Hospital,Ankang 725500,China)

机构地区：[1]安康市平利县医院,陕西安康725500

出　　处：《临床医学研究与实践》2021年第4期40-42,共3页Clinical Research and Practice

摘　　要：目的分析脊柱内固定术后感染的危险因素及对策。方法回顾性分析2015年4月1日至2016年12月31日在本院就诊的120例脊柱内固定手术患者的临床资料,根据术后感染情况分为感染组和非感染组,采用单因素分析法筛选出可能影响脊柱内固定术后感染的因素,随后将所得的结果经Logistic回归进行多因素分析,探讨影响脊柱内固定术后感染的独立风险因素。结果共纳入120例患者,其中感染者15例,未感染者105例。单因素分析结果显示,感染组未规范使用预防性抗生素、术后在ICU进行抢救、脑脊液漏出、大小便失禁、糖尿病、术中使用激素、手术伤口污染的患者占比明显高于非感染组,差异具有统计学意义(P<0.05)。多因素Logistic分析结果显示,未规范使用预防性抗生素、脑脊液漏出、糖尿病、手术伤口污染是影响脊柱内固定术后感染的独立危险因素(P<0.05)。结论脊柱内固定术后感染的独立危险因素包括未规范使用预防性抗生素、脑脊液漏出、糖尿病、手术伤口污染,临床医师需更注意预防存在上述因素的患者发生术后感染。Objective To analyze the risk factors and countermeasures of infection after spinal internal fixation.Methods The clinical data of 120 patients with spinal internal fixation treated in our hospital from April 1,2015 to December 31,2016 were retrospectively analyzed.According to the postoperative infection,the patients were divided into infection group and non-infection group.The univariate analysis method was used to screen out the factors that may affect the postoperative infection of spinal internal fixation,and then the results were analyzed by Logistic regression.The independent risk factors of postoperative infection were determined.Results A total of 120 patients were enrolled,of which 15 cases were infected and 105 cases were uninfected.The results of univariate analysis showed that the proportion of patients non-standard use of prophylactic antibiotics,postoperative rescue in ICU,leakage of cerebrospinal fluid,incontinence of urine and feces,diabetes mellitus,use of hormone during operation,surgical wound pollution in the infection group were significantly higher than those in the non-infection group,and the differences were statistically significant(P<0.05).Multivariate Logistic analysis showed that non-standard use of prophylactic antibiotics,leakage of cerebrospinal fluid,diabetes mellitus,surgical wound pollution were independent risk factors affecting postoperative infection after spinal internal fixation(P<0.05).Conclusion The independent risk factors of infection after spinal internal fixation include non-standard use of prophylactic antibiotics,leakage of cerebrospinal fluid,diabetes mellitus,surgical wound pollution.Clinicians should pay more attentions to prevent postoperative infection in patients with the above factors.

关 键 词：脊柱内固定术 抗生素 感染 脑脊液漏出 糖尿病 手术伤口污染 危险因素 

分 类 号：R68[医药卫生—骨科学]