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作 者:郑方方 ZHENG Fangfang(Department of Cardiology,the Second People’s Hospital of Pingdingshan City,He’nan Pingdingshan 467000,China)
机构地区:[1]平顶山市第二人民医院心内科,河南平顶山467000
出 处:《上海医药》2021年第3期27-29,52,共4页Shanghai Medical & Pharmaceutical Journal
摘 要:目的:探讨普罗帕酮联合电复律治疗心律失常患者炎性因子水平和康复预后的价值。方法:将102例心律失常患者依据随机数字表法分为对照组和观察组各51例。对照组给予胺碘酮治疗,观察组给予普罗帕酮联合电复律治疗,对比两组治疗效果及治疗前后血清超敏C反应蛋白(hs-CRP)、心率变异性(HRV)指标变化情况及不良反应等。结果:观察组治疗总有效率为96.1%,明显高于对照组的78.4(P<0.05),且治疗后观察组血清hs-CRP低于对照组,HRV指标均高于对照组(P<0.05)。结论:普罗帕酮联合电复律治疗心律失常患者能有效提高治疗效果,改善患者心率变异性,降低炎性因子水平。Objective:To investigate the value of propafenone combined with electrocardioversion in the treatment of inflammatory factors of patients with arrhythmia and the effect on their rehabilitation prognosis.Methods:One hundred and two patients with arrhythmia were randomly divided into a control group and an observation group.The control group was treated with amiodarone while the observation group with propafenone combined with electrocardioversion.The therapeutic effect,changes of serum hs-CRP and heart rate variability(HRV)before and after treatment were compared between the two groups.Results:The overall response rate was significantly higher in the observation group than the control group(96.1%vs 78.4%,P<0.05).After treatment,the serum hs-CRP was lower and the indexes of HRV were higher in the observation group than the control group(P<0.05).Conclusion:Propafenone combined with electrocardioversion can improve the therapeutic effect and the HRV and decrease the levels of inflammatory factors in patients with arrhythmia.
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