中国老年男性骨质疏松症影响因素的Meta分析  

Meta-analysis of the influencing factors of osteoporosis in Chinese elderly men

作　　者：夏晓妹 杨士鹏[2] 葛若兰 崔立敏[2] XIA Xiaomei;YANG Shipeng;GE Ruolan;CUI Limin(College of Nursing,Yanbian University,Yanji 133000, China;Department of Orthopaedics,Affiliated Hospital of Yanbian University,Yanji 133000, China)

机构地区：[1]延边大学护理学院,吉林延吉133000 [2]延边大学附属医院骨一科,吉林延吉133000

出　　处：《中国骨质疏松杂志》2021年第2期198-202,共5页Chinese Journal of Osteoporosis

基　　金：吉林省教育厅“十三五”科学技术项目(JJKH20191159KJ)。

摘　　要：目的通过Meta分析明确中国老年男性罹患骨质疏松(osteoporosis,OP)的主要影响因素。方法使用计算机检索中国知网、万方数据库、维普网、PubMed、Web of Science、Embase数据库(自建库以来至2020年1月),并使用NOS进行文献质量评价,使用RevMan 5.3进行Meta分析。结果共纳入21篇研究,提取18个相关的影响因素。Meta分析结果显示,年龄、身高、体重、体质量指数(body mass index,BMI)、骨密度(bone mineral density,BMD)、文化水平、骨折史、血清钙水平、吸烟、日光照射、运动锻炼、饮茶、补钙史、饮牛奶、补维生素D史与我国老年男性罹患OP相关,比较差异有统计学意义(Р<0.05);与饮酒、25-(OH)D水平、血清磷水平方面比较差异无统计学意义(Р>0.05)。结论体重、BMI、BMD、饮牛奶、补钙、补维生素D、血清钙水平、饮茶、运动锻炼、日光照射及文化水平是我国老年男性罹患OP的保护因素;年龄、身高降低、吸烟、骨折史是危险因素;饮酒、25-(OH)D水平、血清磷水平需进一步验证。Objective To identify the main influencing factors of OP in the elderly men in China through Meta-analysis.Methods The literatures of CNKI,Wanfang Database,VIP Network,PubMed,Web of Science,Embase Database(from inception to January 2020)were screened.The quality was evaluated according to NOS.Meta-analysis was performed using a RevMan5.3 software.Results A total of 21 reference were included,18 influencing factors were extracted.Meta-analysis showed that age,height,weight,BMI,BMD,education level,fracture history,serum calcium level,smoking,sunlight exposure,exercise,drinking tea,calcium supplement history,drinking milk and vitamin D supplementation history were associated with OP,and the differences were statistically significant(P<0.05).There were no statistically significant(P>0.05)in drinking,25-(OH)D and serum phosphorus level.Conclusion Body weight,BMI,BMD,milk drinking,calcium supplement,vitamin D supplement,serum calcium level,tea drinking,exercise,sunlight exposure and cultural level were protective factors;age,loss of height,smoking and fracture history were the risk factors;The factors of drinking,25-(OH)D and serum phosphorus level need to be further vertified.

关 键 词：老年男性 骨质疏松症 影响因素 META分析 

分 类 号：R580[医药卫生—内分泌]